Leuprolide acetate and Eschar - a phase IV clinical study of FDA data
Summary:
Eschar is reported as a side effect among people who take Leuprolide acetate (leuprolide acetate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Alprazolam, and have Arteriosclerosis coronary artery.
The phase IV clinical study analyzes which people have Eschar when taking Leuprolide acetate. It is created by eHealthMe based on reports of 6,881 people who have side effects when taking Leuprolide acetate from the FDA, and is updated regularly.
What is Leuprolide acetate?
Leuprolide acetate has active ingredients of leuprolide acetate. eHealthMe is studying from 6,910 Leuprolide acetate users. Check the latest studies of Leuprolide acetate.
What is Eschar?
Eschar (dead tissue that falls off (sheds) from healthy skin) is found to be associated with 151 drugs and 337 conditions by eHealthMe. Check the latest studies of Eschar.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
6,881 people reported to have side effects when taking Leuprolide acetate.
Among them, 13 people (0.19%) have Eschar.

Among these 13 people:
How long have people been on Leuprolide acetate when they have Eschar? *
- < 1 month: 60 %
- 1 - 6 months: 40 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Eschar when taking Leuprolide acetate? *
- female: 23.08 %
- male: 76.92 %
What is the age of people who have Eschar when taking Leuprolide acetate? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 20 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 80 %
What are other drugs people take besides Leuprolide acetate? *
- Trusopt: 7 people, 53.85%
- Enzalutamide: 7 people, 53.85%
- Bicalutamide: 7 people, 53.85%
- Dexamethasone: 7 people, 53.85%
- Alprazolam: 7 people, 53.85%
- Prednisone: 4 people, 30.77%
- Pentoxifylline: 3 people, 23.08%
- Telmisartan: 3 people, 23.08%
- Trospium Chloride: 3 people, 23.08%
- Bisoprolol Fumarate: 3 people, 23.08%
What are other side effects people have besides Eschar? *
- Weakness: 7 people, 53.85%
- Osgood-Schlatter Disease (an overuse injury that occurs in the knee area of growing adolescents. it is caused by inflammation of the tendon below the kneecap): 7 people, 53.85%
- Anaemia (lack of blood): 7 people, 53.85%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 53.85%
- Diarrhea: 7 people, 53.85%
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 7 people, 53.85%
- Gynecomastia (enlargement of the gland tissue of the male breast): 7 people, 53.85%
- Urination - Excessive Volume: 7 people, 53.85%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 53.85%
- Thrombocytopenia (decrease of platelets in blood): 7 people, 53.85%
What are the existing conditions these people have? *
- Prostate Cancer Metastatic: 7 people, 53.85%
- Insomnia (sleeplessness): 7 people, 53.85%
- Glaucoma (increased fluid pressure in the eye with vision loss): 7 people, 53.85%
- Enlarged Prostate: 7 people, 53.85%
- Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 7 people, 53.85%
- Prostate Cancer: 6 people, 46.15%
- Precocious Puberty: 3 people, 23.08%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
- High Blood Pressure: 1 person, 7.69%
- Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Leuprolide acetate and have Eschar?
- Check whether Eschar is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Leuprolide acetate:
- Leuprolide acetate (6,910 reports)
Eschar treatments and more:
- Eschar (989 reports)
How severe was Eschar and when was it recovered:
Expand to all the drugs that have ingredients of leuprolide acetate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Leuprolide acetate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Eschar:
- Eschar (151 drugs)
Browse all the conditions that are associated with Eschar:
- Eschar (337 conditions)
Related publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Leuprolide acetate) and Leuprolide acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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