Levetiracetam and Aphonia - a phase IV clinical study of FDA data

Summary:

Aphonia is reported as a side effect among people who take Levetiracetam (levetiracetam), especially for people who are female, 60+ old, also take Tolterodine, and have Depression.

The phase IV clinical study analyzes which people have Aphonia when taking Levetiracetam. It is created by eHealthMe based on reports of 74,747 people who have side effects when taking Levetiracetam from the FDA, and is updated regularly.

What is Levetiracetam?

Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 75,292 Levetiracetam users. Check the latest studies of Levetiracetam.

What is Aphonia?

Aphonia (inability to produce voice) is found to be associated with 888 drugs and 840 conditions by eHealthMe. Check the latest studies of Aphonia.

On Jul, 11, 2026

74,747 people reported to have side effects when taking Levetiracetam.
Among them, 27 people (0.04%) have Aphonia.

Among these 27 people:

What is the gender of people who have Aphonia when taking Levetiracetam? *

female: 100 %
male: 0.0 %

What is the age of people who have Aphonia when taking Levetiracetam? *

What are other drugs people take besides Levetiracetam? *

What are other side effects people have besides Aphonia? *

Hoarseness Or Changing Voice: 17 people, 62.96%
Confusional State: 15 people, 55.56%
Drug Ineffective: 14 people, 51.85%
Fever: 11 people, 40.74%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 9 people, 33.33%
Weakness: 6 people, 22.22%
High Blood Pressure: 6 people, 22.22%
Arrhythmias (irregular heartbeat): 5 people, 18.52%
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 5 people, 18.52%
Fatigue (feeling of tiredness): 5 people, 18.52%

What are the existing conditions these people have? *

Depression: 12 people, 44.44%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 9 people, 33.33%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 33.33%
Pain: 9 people, 33.33%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 11.11%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 11.11%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 11.11%
Lung Carcinoma Cell Type Unspecified Stage Iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 3.70%
Dizziness: 1 person, 3.70%
High Blood Pressure: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Levetiracetam and have Aphonia?

- Check whether Aphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levetiracetam:

Levetiracetam (75,292 reports)

Aphonia treatments and more:

Aphonia (15,979 reports)

Browse all side effects of Levetiracetam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphonia:

Aphonia (888 drugs)

Browse all the conditions that are associated with Aphonia:

Aphonia (840 conditions)

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam (the active ingredients of Levetiracetam) and Levetiracetam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.