Levoleucovorin calcium and Diverticulitis - a phase IV clinical study of FDA data

Summary:

Diverticulitis is reported as a side effect among people who take Levoleucovorin calcium (levoleucovorin calcium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dexamethasone, and have Adenocarcinoma pancreas.

The phase IV clinical study analyzes which people have Diverticulitis when taking Levoleucovorin calcium. It is created by eHealthMe based on reports of 2,464 people who have side effects when taking Levoleucovorin calcium from the FDA, and is updated regularly.

What is Levoleucovorin calcium?

Levoleucovorin calcium has active ingredients of levoleucovorin calcium. eHealthMe is studying from 2,464 Levoleucovorin calcium users. Check the latest studies of Levoleucovorin calcium.

What is Diverticulitis?

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall) is found to be associated with 1,362 drugs and 1,360 conditions by eHealthMe. Check the latest studies of Diverticulitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

2,464 people reported to have side effects when taking Levoleucovorin calcium.
Among them, 12 people (0.49%) have Diverticulitis.

Could Levoleucovorin calcium cause Diverticulitis?

Among these 12 people:

How long have people been on Levoleucovorin calcium when they have Diverticulitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diverticulitis when taking Levoleucovorin calcium? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Diverticulitis when taking Levoleucovorin calcium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Levoleucovorin calcium? *

  1. Oxaliplatin: 12 people, 100.00%
  2. Fluorouracil: 12 people, 100.00%
  3. Dexamethasone: 12 people, 100.00%
  4. Ondansetron: 11 people, 91.67%
  5. Chlorpheniramine Maleate: 10 people, 83.33%
  6. Metformin Hydrochloride: 6 people, 50.00%
  7. Metformin: 5 people, 41.67%
  8. Zolpidem Tartrate: 1 person, 8.33%
  9. Rosuvastatin Calcium: 1 person, 8.33%
  10. Palonosetron Hydrochloride: 1 person, 8.33%

What are other side effects people have besides Diverticulitis? *

  1. Diarrhea Haemorrhagic: 11 people, 91.67%
  2. Abdominal Pain: 11 people, 91.67%

What are the existing conditions these people have? *

  1. Adenocarcinoma Pancreas (cancer of pancreas): 11 people, 91.67%
  2. Insomnia (sleeplessness): 1 person, 8.33%
  3. High Blood Pressure: 1 person, 8.33%
  4. High Blood Cholesterol: 1 person, 8.33%
  5. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 8.33%
  6. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 8.33%
  7. Cancer Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Levoleucovorin calcium and have Diverticulitis?

- Check whether Diverticulitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levoleucovorin calcium:

Diverticulitis treatments and more:

How severe was Diverticulitis and when was it recovered:

Expand to all the drugs that have ingredients of levoleucovorin calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levoleucovorin calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diverticulitis:

Browse all the conditions that are associated with Diverticulitis:


How the study uses the data?

The study uses data from the FDA. It is based on levoleucovorin calcium (the active ingredients of Levoleucovorin calcium) and Levoleucovorin calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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