Levonorgestrel and Menstruation irregular - a phase IV clinical study of FDA data

Summary:

Menstruation irregular is reported as a side effect among people who take Levonorgestrel (levonorgestrel), especially for people who are 20-29 old, have been taking the drug for < 1 month also take Plan B One-Step, and have Headache.

The phase IV clinical study analyzes which people have Menstruation irregular when taking Levonorgestrel. It is created by eHealthMe based on reports of 3,996 people who have side effects when taking Levonorgestrel from the FDA, and is updated regularly.

What is Levonorgestrel?

Levonorgestrel has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 4,186 Levonorgestrel users. Check the latest studies of Levonorgestrel.

What is Menstruation irregular?

Menstruation irregular is found to be associated with 620 drugs and 912 conditions by eHealthMe. Check the latest studies of Menstruation irregular.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,996 people reported to have side effects when taking Levonorgestrel.
Among them, 76 people (1.9%) have Menstruation irregular.

Could Levonorgestrel cause Menstruation irregular?

Among these 76 people:

How long have people been on Levonorgestrel when they have Menstruation irregular? *

What is the age of people who have Menstruation irregular when taking Levonorgestrel? *

What are other drugs people take besides Levonorgestrel? *

What are other side effects people have besides Menstruation irregular? *

Nausea (feeling of having an urge to vomit): 10 people, 13.16%
Headache (pain in head): 10 people, 13.16%
Abdominal Pain: 7 people, 9.21%
Muscle Spasms (muscle contraction): 7 people, 9.21%
Nausea And Vomiting: 6 people, 7.89%
Heavy Or Prolong Menstrual Bleeding: 6 people, 7.89%
Fatigue (feeling of tiredness): 6 people, 7.89%
Dysmenorrhea (painful menstruation): 5 people, 6.58%
Vaginal Bleeding Between Periods: 5 people, 6.58%
Dizziness: 5 people, 6.58%

What are the existing conditions these people have? *

Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 2 people, 2.63%
Headache (pain in head): 2 people, 2.63%
Seasonal Allergy (allergic condition due to certain season): 1 person, 1.32%
Pain: 1 person, 1.32%
Hereditary Angioedema (recurrent episodes of severe swelling): 1 person, 1.32%
Heavy Or Prolong Menstrual Bleeding: 1 person, 1.32%
Cardiac Failure Chronic: 1 person, 1.32%
Cardiac Failure Acute: 1 person, 1.32%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 1.32%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 1.32%

* Approximation only. Some reports may have incomplete information.

Do you take Levonorgestrel and have Menstruation irregular?

- Check whether Menstruation irregular is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levonorgestrel:

Levonorgestrel (4,186 reports)

Browse all side effects of Levonorgestrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Menstruation irregular:

Menstruation irregular (620 drugs)

Browse all the conditions that are associated with Menstruation irregular:

Menstruation irregular (912 conditions)

Related publications that referenced our studies

Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Levonorgestrel) and Levonorgestrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.