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Levonorgestrel and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Levonorgestrel (levonorgestrel), especially for people who are female, 40-49 old, also take Colecalciferol, and have Celiac disease - sprue.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Levonorgestrel. It is created by eHealthMe based on reports of 3,996 people who have side effects when taking Levonorgestrel from the FDA, and is updated regularly.

What is Levonorgestrel?

Levonorgestrel has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 4,186 Levonorgestrel users. Check the latest studies of Levonorgestrel.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,087 drugs and 1,361 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

On Jul, 11, 2026

3,996 people reported to have side effects when taking Levonorgestrel.
Among them, 15 people (0.38%) have Multiple sclerosis.

Could Levonorgestrel cause Multiple sclerosis?

Among these 15 people:

What is the gender of people who have Multiple sclerosis when taking Levonorgestrel? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Multiple sclerosis when taking Levonorgestrel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 21.43 %
  • 30-39: 0.0 %
  • 40-49: 78.57 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Levonorgestrel? *

  1. Colecalciferol: 7 people, 46.67%
  2. Lemtrada: 3 people, 20.00%
  3. Acyclovir: 2 people, 13.33%
  4. Valacyclovir Hydrochloride: 2 people, 13.33%
  5. Pantoprazole Sodium: 2 people, 13.33%
  6. Folic Acid: 2 people, 13.33%
  7. Gilenya: 2 people, 13.33%
  8. Lyrica: 1 person, 6.67%
  9. Amitiza: 1 person, 6.67%
  10. Ampyra: 1 person, 6.67%

What are other side effects people have besides Multiple sclerosis? *

  1. Hypotension (abnormally low blood pressure): 10 people, 66.67%
  2. Hyperglycemia (high blood sugar): 9 people, 60.00%
  3. Hypersensitivity: 9 people, 60.00%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 60.00%
  5. Dizziness: 9 people, 60.00%
  6. Electrocardiogram Abnormal: 9 people, 60.00%
  7. Headache (pain in head): 9 people, 60.00%
  8. Fatigue (feeling of tiredness): 9 people, 60.00%
  9. C-Reactive Protein Increased: 8 people, 53.33%
  10. Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 8 people, 53.33%

What are the existing conditions these people have? *

  1. Celiac Disease - Sprue (a disease of the small intestine): 9 people, 60.00%
  2. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 8 people, 53.33%
  3. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 33.33%
  4. Weight Loss: 1 person, 6.67%
  5. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 6.67%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.67%
  7. Pain: 1 person, 6.67%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Levonorgestrel and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levonorgestrel:

Multiple sclerosis treatments and more:

How severe was Multiple sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of levonorgestrel:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levonorgestrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Browse all the conditions that are associated with Multiple sclerosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Levonorgestrel) and Levonorgestrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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