Levothroid and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Levothroid (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Synthroid, and have Stomatitis.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Levothroid. It is created by eHealthMe based on reports of 8,088 people who have side effects when taking Levothroid from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,973 Levothroid users. Check the latest studies of Levothroid.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,040 drugs and 1,419 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Dec, 26, 2025

8,088 people reported to have side effects when taking Levothroid.
Among them, 16 people (0.2%) have Hyperthyroidism.

Among these 16 people:

How long have people been on Levothroid when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Levothroid? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Hyperthyroidism when taking Levothroid? *

What are other drugs people take besides Levothroid? *

What are other side effects people have besides Hyperthyroidism? *

Weakness: 4 people, 25.00%
Fatigue (feeling of tiredness): 4 people, 25.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 18.75%
Acute Kidney Failure: 2 people, 12.50%
Memory Loss: 2 people, 12.50%
Mania (a state of abnormally elevated or irritable mood): 2 people, 12.50%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 2 people, 12.50%
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 2 people, 12.50%
Hypokalemia (low potassium): 2 people, 12.50%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 12.50%

What are the existing conditions these people have? *

Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 6.25%
Heart Rate Irregular: 1 person, 6.25%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 6.25%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%
Depression: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 6.25%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 6.25%
Stomatitis (inflammation of mucous membrane of mouth): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothroid:

Levothroid (8,973 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,827 reports)

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,040 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,419 conditions)

Drugs similar to Levothroid and Hyperthyroidism :

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothroid) and Levothroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.