Levothroid and Sedation - a phase IV clinical study of FDA data

Summary:

Sedation is reported as a side effect among people who take Levothroid (levothyroxine sodium), especially for people who are female, 60+ old, also take Premarin, and have High blood pressure.

The phase IV clinical study analyzes which people have Sedation when taking Levothroid. It is created by eHealthMe based on reports of 8,088 people who have side effects when taking Levothroid from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,973 Levothroid users. Check the latest studies of Levothroid.

What is Sedation?

Sedation is found to be associated with 1,399 drugs and 1,272 conditions by eHealthMe. Check the latest studies of Sedation.

On Nov, 22, 2025

8,088 people reported to have side effects when taking Levothroid.
Among them, 41 people (0.51%) have Sedation.

Among these 41 people:

What is the gender of people who have Sedation when taking Levothroid? *

female: 87.18 %
male: 12.82 %

What is the age of people who have Sedation when taking Levothroid? *

What are other drugs people take besides Levothroid? *

What are other side effects people have besides Sedation? *

Fatigue (feeling of tiredness): 10 people, 24.39%
Drowsiness: 6 people, 14.63%
Fall: 4 people, 9.76%
Nausea (feeling of having an urge to vomit): 3 people, 7.32%
Excoriation (to tear or wear off the skin of): 3 people, 7.32%
Cardiovascular Insufficiency (inadequate functioning of heart): 3 people, 7.32%
Muscle Tightness: 3 people, 7.32%
Decreased Activity: 3 people, 7.32%
Feelings Of Worthlessness: 3 people, 7.32%
Orgasm Abnormal (abnormal sex satisfaction): 3 people, 7.32%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 12.20%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 7.32%
Osteoporosis (bones weak and more likely to break): 3 people, 7.32%
Orgasm Abnormal (abnormal sex satisfaction): 3 people, 7.32%
Primary Hypothyroidism (failure of the thyroid gland to produce or release thyroid hormones into the bloodstream): 2 people, 4.88%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 4.88%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 4.88%
Herniated Nucleus Pulposus (Slipped Disk): 2 people, 4.88%
Sleep Disorder: 2 people, 4.88%
Menopausal Symptoms: 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and have Sedation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothroid:

Levothroid (8,973 reports)

Sedation treatments and more:

Sedation (52,223 reports)

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation:

Sedation (1,399 drugs)

Browse all the conditions that are associated with Sedation:

Sedation (1,272 conditions)

Drugs similar to Levothroid and Sedation :

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothroid) and Levothroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.