Levoxyl and Interstitial nephritis - a phase IV clinical study of FDA data

Summary:

Interstitial nephritis is reported as a side effect among people who take Levoxyl (levothyroxine sodium), especially for people who are female, 60+ old, also take Prilosec, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Interstitial nephritis when taking Levoxyl. It is created by eHealthMe based on reports of 23,566 people who have side effects when taking Levoxyl from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Interstitial nephritis?

Interstitial nephritis (inflammation of the kidney) is found to be associated with 1,094 drugs and 1,566 conditions by eHealthMe. Check the latest studies of Interstitial nephritis.

On Jul, 10, 2026

23,566 people reported to have side effects when taking Levoxyl.
Among them, 24 people (0.1%) have Interstitial nephritis.

Could Levoxyl cause Interstitial nephritis?

Among these 24 people:

What is the gender of people who have Interstitial nephritis when taking Levoxyl? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Interstitial nephritis when taking Levoxyl? *

What are other drugs people take besides Levoxyl? *

What are other side effects people have besides Interstitial nephritis? *

Acute Kidney Failure: 15 people, 62.50%
Chronic Kidney Disease: 15 people, 62.50%
Renal Injury (kidney injury): 6 people, 25.00%
Indigestion: 4 people, 16.67%
Nephrogenic Anaemia (anaemia due to kidney disease): 3 people, 12.50%
Fatigue (feeling of tiredness): 3 people, 12.50%
Renal Tubular Necrosis (death of kidney tubules): 3 people, 12.50%
Weight Decreased: 2 people, 8.33%
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 2 people, 8.33%
Haemoglobin Decreased: 2 people, 8.33%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 75.00%
High Blood Pressure: 9 people, 37.50%
High Blood Cholesterol: 7 people, 29.17%
Pain: 4 people, 16.67%
Erection Problems: 4 people, 16.67%
Infection: 4 people, 16.67%
Diabetes: 4 people, 16.67%
Asthma: 3 people, 12.50%
Headache (pain in head): 3 people, 12.50%
Neuralgia (pain in one or more nerves): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Levoxyl and have Interstitial nephritis?

- Check whether Interstitial nephritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levoxyl:

Levoxyl (25,178 reports)

Browse all side effects of Levoxyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial nephritis:

Interstitial nephritis (1,094 drugs)

Browse all the conditions that are associated with Interstitial nephritis:

Interstitial nephritis (1,566 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levoxyl) and Levoxyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.