Levoxyl and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Levoxyl (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Synthroid, and have Osteoporosis.

The phase IV clinical study analyzes which people have Sciatica when taking Levoxyl. It is created by eHealthMe based on reports of 23,566 people who have side effects when taking Levoxyl from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,176 Levoxyl users. Check the latest studies of Levoxyl.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,146 drugs and 1,427 conditions by eHealthMe. Check the latest studies of Sciatica.

On Mar, 09, 2026

23,566 people reported to have side effects when taking Levoxyl.
Among them, 73 people (0.31%) have Sciatica.

Among these 73 people:

* Approximation only. Some reports may have incomplete information.

Do you take Levoxyl and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levoxyl:

Levoxyl (25,176 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

How severe was Sciatica and when was it recovered:

Sciatica in Levoxyl

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sciatica and drugs with ingredients of levothyroxine sodium (1,988 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levoxyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,146 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,427 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levoxyl) and Levoxyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.