Levulan and Photosensitivity reaction - a phase IV clinical study of FDA data

Summary:

Photosensitivity reaction is reported as a side effect among people who take Levulan (aminolevulinic acid hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Accupril, and have Actinic keratosis.

The phase IV clinical study analyzes which people have Photosensitivity reaction when taking Levulan. It is created by eHealthMe based on reports of 1,163 people who have side effects when taking Levulan from the FDA, and is updated regularly.

What is Levulan?

Levulan has active ingredients of aminolevulinic acid hydrochloride. eHealthMe is studying from 1,168 Levulan users. Check the latest studies of Levulan.

What is Photosensitivity reaction?

Photosensitivity reaction is found to be associated with 1,046 drugs and 1,262 conditions by eHealthMe. Check the latest studies of Photosensitivity reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

1,163 people reported to have side effects when taking Levulan.
Among them, 21 people (1.81%) have Photosensitivity reaction.

Could Levulan cause Photosensitivity reaction?

Among these 21 people:

How long have people been on Levulan when they have Photosensitivity reaction? *

What is the gender of people who have Photosensitivity reaction when taking Levulan? *

female: 61.11 %
male: 38.89 %

What is the age of people who have Photosensitivity reaction when taking Levulan? *

What are other drugs people take besides Levulan? *

Tylenol: 1 person, 4.76%
Lisinopril: 1 person, 4.76%
Hydrochlorothiazide: 1 person, 4.76%
Aleve: 1 person, 4.76%
Accupril: 1 person, 4.76%

What are other side effects people have besides Photosensitivity reaction? *

Eye Irritation: 2 people, 9.52%
Application Site Erythema (redness of the skin at application site): 2 people, 9.52%
Scar: 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%
Itching: 2 people, 9.52%
Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 1 person, 4.76%
Eye Disorder: 1 person, 4.76%
Discomfort: 1 person, 4.76%
Dermatitis Psoriasiform (large white or silver flakes on the skin): 1 person, 4.76%
Dermatitis Lichenoid (lichen simplex chronicus is a chronic inflammation of the skin): 1 person, 4.76%

What are the existing conditions these people have? *

Actinic Keratosis (skin disease due to sun exposure): 7 people, 33.33%
Rashes (redness): 1 person, 4.76%
Precancerous Skin Lesion: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Levulan and have Photosensitivity reaction?

- Check whether Photosensitivity reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levulan:

Levulan (1,168 reports)

Photosensitivity reaction treatments and more:

Photosensitivity reaction (19,066 reports)

How severe was Photosensitivity reaction and when was it recovered:

Photosensitivity reaction in Levulan

Expand to all the drugs that have ingredients of aminolevulinic acid hydrochloride:

Photosensitivity reaction and drugs with ingredients of aminolevulinic acid hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levulan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Photosensitivity reaction:

Photosensitivity reaction (1,046 drugs)

Browse all the conditions that are associated with Photosensitivity reaction:

Photosensitivity reaction (1,262 conditions)

Related publications that referenced our studies

Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on aminolevulinic acid hydrochloride (the active ingredients of Levulan) and Levulan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.