Lialda and Dry mouth - a phase IV clinical study of FDA data

Summary:

Dry mouth is reported as a side effect among people who take Lialda (mesalamine), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Vitamin D, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Dry mouth when taking Lialda. It is created by eHealthMe based on reports of 9,821 people who have side effects when taking Lialda from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Dry mouth?

Dry mouth is found to be associated with 2,089 drugs and 2,492 conditions by eHealthMe. Check the latest studies of Dry mouth.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

9,821 people reported to have side effects when taking Lialda.
Among them, 25 people (0.25%) have Dry mouth.

Among these 25 people:

How long have people been on Lialda when they have Dry mouth? *

What is the gender of people who have Dry mouth when taking Lialda? *

female: 56 %
male: 44 %

What is the age of people who have Dry mouth when taking Lialda? *

What are other drugs people take besides Lialda? *

What are other side effects people have besides Dry mouth? *

Diarrhea: 6 people, 24.00%
Glossodynia (a burning or painful sensation in the tongue): 4 people, 16.00%
Memory Loss: 4 people, 16.00%
Fatigue (feeling of tiredness): 3 people, 12.00%
Disturbance In Attention: 3 people, 12.00%
Lip Pain: 3 people, 12.00%
Joint Pain: 3 people, 12.00%
Chest Pain: 2 people, 8.00%
Dry Eyes (lack of adequate tears): 2 people, 8.00%
Dizziness Postural: 2 people, 8.00%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.00%
Breast Cancer Stage Iv: 3 people, 12.00%
Depression: 3 people, 12.00%
High Blood Cholesterol: 3 people, 12.00%
Cardiac Disorder: 2 people, 8.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.00%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 8.00%
Type 2 Diabetes: 1 person, 4.00%
Adverse Drug Reaction: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and have Dry mouth?

- Check whether Dry mouth is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lialda:

Lialda (10,199 reports)

Dry mouth treatments and more:

Dry mouth (97,956 reports)

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dry mouth:

Dry mouth (2,089 drugs)

Browse all the conditions that are associated with Dry mouth:

Dry mouth (2,492 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Lialda) and Lialda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.