Librium and Agitation - a phase IV clinical study of FDA data

Summary:

Agitation is reported as a side effect among people who take Librium (chlordiazepoxide hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Pain.

The phase IV clinical study analyzes which people have Agitation when taking Librium. It is created by eHealthMe based on reports of 2,250 people who have side effects when taking Librium from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Agitation?

Agitation (state of anxiety or nervous excitement) is found to be associated with 2,284 drugs and 3,316 conditions by eHealthMe. Check the latest studies of Agitation.

On Aug, 04, 2026

2,250 people reported to have side effects when taking Librium.
Among them, 73 people (3.24%) have Agitation.

Among these 73 people:

How long have people been on Librium when they have Agitation? *

What is the gender of people who have Agitation when taking Librium? *

female: 38.36 %
male: 61.64 %

What is the age of people who have Agitation when taking Librium? *

What are other drugs people take besides Librium? *

What are other side effects people have besides Agitation? *

Hyperhidrosis (abnormally increased sweating): 26 people, 35.62%
Insomnia (sleeplessness): 23 people, 31.51%
Dyspnea (difficult or laboured breathing): 22 people, 30.14%
Pain: 22 people, 30.14%
Confusion: 19 people, 26.03%
Nausea (feeling of having an urge to vomit): 19 people, 26.03%
Fall: 18 people, 24.66%
Drowsiness: 17 people, 23.29%
Malaise (a feeling of general discomfort or uneasiness): 17 people, 23.29%
Hallucinations (sensations that appear real but are created by your mind): 17 people, 23.29%

What are the existing conditions these people have? *

Pain: 13 people, 17.81%
Depression: 8 people, 10.96%
Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 6.85%
Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 6.85%
Ulcer Haemorrhage (bleeding ulcer): 5 people, 6.85%
Parkinson's Disease: 4 people, 5.48%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 5.48%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 4.11%
Quit Smoking: 3 people, 4.11%
Poor Quality Sleep: 2 people, 2.74%

* Approximation only. Some reports may have incomplete information.

Do you take Librium and have Agitation?

- Check whether Agitation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Librium:

Librium (2,490 reports)

Agitation treatments and more:

Agitation (142,108 reports)

How severe was Agitation and when was it recovered:

Agitation in Librium

Expand to all the drugs that have ingredients of chlordiazepoxide hydrochloride:

Agitation and drugs with ingredients of chlordiazepoxide hydrochloride (136 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Agitation:

Agitation (2,284 drugs)

Browse all the conditions that are associated with Agitation:

Agitation (3,316 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride (the active ingredients of Librium) and Librium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.