Librium and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Librium (chlordiazepoxide hydrochloride), especially for people who are male, 60+ old, also take Celexa, and have Depression.

The study is created by eHealthMe based on reports of 2,250 people who have side effects when taking Librium from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

On Apr, 21, 2026

2,250 people reported to have side effects when taking Librium.
Among them, 37 people (1.64%) died.

Among these 37 people:

What is the gender of people who died when taking Librium? *

female: 50 %
male: 50 %

What is the age of people who died when taking Librium? *

What are other drugs people take besides Librium? *

What are other side effects people have before they died? *

Fatigue (feeling of tiredness): 6 people, 16.22%
Back Pain: 5 people, 13.51%
Weakness: 4 people, 10.81%
Gait Disturbance: 4 people, 10.81%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 10.81%
Nausea And Vomiting: 3 people, 8.11%
Diarrhea: 3 people, 8.11%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 8.11%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 8.11%
Pain: 3 people, 8.11%

What are the existing conditions these people have? *

Depression: 4 people, 10.81%
Affective Disorder (mental disorder): 3 people, 8.11%
Post-Traumatic Stress Disorder: 3 people, 8.11%
Neoplasm Malignant (cancer tumour): 2 people, 5.41%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 2.70%
Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 2.70%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 2.70%
Cardiomyopathy (weakening of the heart muscle): 1 person, 2.70%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Librium:

Librium (2,490 reports)

Expand to all the drugs that have ingredients of chlordiazepoxide hydrochloride:

Death and drugs with ingredients of chlordiazepoxide hydrochloride (201 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,159 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride (the active ingredients of Librium) and Librium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.