Librium and Parkinson's disease - a phase IV clinical study of FDA data

Summary:

Parkinson's disease is reported as a side effect among people who take Librium (chlordiazepoxide hydrochloride), especially for people who are male, 60+ old, also take Sinemet, and have Glaucoma.

The phase IV clinical study analyzes which people have Parkinson's disease when taking Librium. It is created by eHealthMe based on reports of 2,250 people who have side effects when taking Librium from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Parkinson's disease?

Parkinson's disease is found to be associated with 1,113 drugs and 1,629 conditions by eHealthMe. Check the latest studies of Parkinson's disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

2,250 people reported to have side effects when taking Librium.
Among them, 12 people (0.53%) have Parkinson's disease.

Could Librium cause Parkinson's disease?

Among these 12 people:

What is the gender of people who have Parkinson's disease when taking Librium? *

female: 8.33 %
male: 91.67 %

What is the age of people who have Parkinson's disease when taking Librium? *

What are other drugs people take besides Librium? *

What are other side effects people have besides Parkinson's disease? *

Hypotension (abnormally low blood pressure): 5 people, 41.67%
Drug Ineffective: 4 people, 33.33%
Gait Disturbance: 4 people, 33.33%
Freezing Phenomenon: 4 people, 33.33%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 33.33%
Dehydration (dryness resulting from the removal of water): 4 people, 33.33%
Loss Of Consciousness: 4 people, 33.33%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 33.33%
Weight Decreased: 3 people, 25.00%
Overdose: 3 people, 25.00%

What are the existing conditions these people have? *

Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 33.33%
Ulcer Haemorrhage (bleeding ulcer): 3 people, 25.00%
Dyskinesia (abnormality or impairment of voluntary movement): 3 people, 25.00%
Back Pain: 2 people, 16.67%
Depression: 2 people, 16.67%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 16.67%
Thinking Abnormal: 1 person, 8.33%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 8.33%
Bipolar Disorder (mood disorder): 1 person, 8.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Librium and have Parkinson's disease?

- Check whether Parkinson's disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Librium:

Librium (2,490 reports)

Parkinson's disease treatments and more:

Parkinson's disease (151,258 reports)

How severe was Parkinson's disease and when was it recovered:

Parkinson's disease in Librium

Expand to all the drugs that have ingredients of chlordiazepoxide hydrochloride:

Parkinson's disease and drugs with ingredients of chlordiazepoxide hydrochloride (21 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Parkinson's disease:

Parkinson's disease (1,113 drugs)

Browse all the conditions that are associated with Parkinson's disease:

Parkinson's disease (1,629 conditions)

Related publications that referenced our studies

Woulfe JM, Gray MT, Gray DA, Munoz DG, Middeldorp JM, "Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease", Parkinsonism & related disorders, 2014 Jul .
Woulfe JM, Gray MT, Gray DA, Munoz DG, Middeldorp JM, "Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease", Parkinsonism & related disorders, 2014 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride (the active ingredients of Librium) and Librium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.