Librium and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Librium (chlordiazepoxide hydrochloride), especially for people who are female, 60+ old, also take Neurontin, and have High blood pressure.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Librium. It is created by eHealthMe based on reports of 2,250 people who have side effects when taking Librium from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,201 drugs and 1,697 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

On Aug, 23, 2025

2,250 people reported to have side effects when taking Librium.
Among them, 19 people (0.84%) have Peripheral swelling.

Could Librium cause Peripheral swelling?

Among these 19 people:

What is the gender of people who have Peripheral swelling when taking Librium? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Peripheral swelling when taking Librium? *

What are other drugs people take besides Librium? *

What are other side effects people have besides Peripheral swelling? *

Joint Swelling: 12 people, 63.16%
Back Pain: 9 people, 47.37%
Weight Increased: 7 people, 36.84%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 26.32%
High Blood Pressure: 4 people, 21.05%
Lipoma (a growth of fatty tissue that slowly develops just under your skin): 4 people, 21.05%
Negative Thoughts: 4 people, 21.05%
Nerve Compression: 4 people, 21.05%
Oropharyngeal Pain: 4 people, 21.05%
Pain: 4 people, 21.05%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 31.58%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 4 people, 21.05%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 4 people, 21.05%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
Neuropathy Peripheral (surface nerve damage): 2 people, 10.53%
Neuralgia (pain in one or more nerves): 2 people, 10.53%
Depression: 2 people, 10.53%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 2 people, 10.53%
Sleep Disorder: 2 people, 10.53%
Vascular Fragility (high risk of complications from surgery): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Librium and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Librium:

Librium (2,490 reports)

Peripheral swelling treatments and more:

Peripheral swelling (168,738 reports)

How severe was Peripheral swelling and when was it recovered:

Peripheral swelling in Librium

Expand to all the drugs that have ingredients of chlordiazepoxide hydrochloride:

Peripheral swelling and drugs with ingredients of chlordiazepoxide hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,201 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,697 conditions)

Drugs similar to Librium and Peripheral swelling :

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride (the active ingredients of Librium) and Librium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.