Librium and Spinal osteoarthritis - a phase IV clinical study of FDA data

Summary:

Spinal osteoarthritis is reported as a side effect among people who take Librium (chlordiazepoxide hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Premarin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Spinal osteoarthritis when taking Librium. It is created by eHealthMe based on reports of 2,250 people who have side effects when taking Librium from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Spinal osteoarthritis?

Spinal osteoarthritis (joint cartilage loss in spine) is found to be associated with 1,418 drugs and 1,125 conditions by eHealthMe. Check the latest studies of Spinal osteoarthritis.

On Jul, 25, 2026

2,250 people reported to have side effects when taking Librium.
Among them, 26 people (1.16%) have Spinal osteoarthritis.

Could Librium cause Spinal osteoarthritis?

Among these 26 people:

How long have people been on Librium when they have Spinal osteoarthritis? *

What is the gender of people who have Spinal osteoarthritis when taking Librium? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Spinal osteoarthritis when taking Librium? *

What are other drugs people take besides Librium? *

What are other side effects people have besides Spinal osteoarthritis? *

Diarrhea: 18 people, 69.23%
Fall: 17 people, 65.38%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 17 people, 65.38%
Memory Loss: 17 people, 65.38%
Tinnitus (a ringing in the ears): 17 people, 65.38%
Hot Flush (sudden feelings of heat): 16 people, 61.54%
Lacunar Infarction (a type of stroke): 16 people, 61.54%
Cerebral Ischaemia (insufficient blood flow to the brain to meet metabolic demand): 16 people, 61.54%
Cerebral Atrophy (decrement in size of brain): 16 people, 61.54%
Cardiac Flutter (abnormal heart rhythm): 16 people, 61.54%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 15.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 15.38%
Thyroid Diseases: 3 people, 11.54%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 11.54%
Depression: 3 people, 11.54%
High Blood Cholesterol: 3 people, 11.54%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.69%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 7.69%
Hypersensitivity: 2 people, 7.69%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Librium and have Spinal osteoarthritis?

- Check whether Spinal osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Librium:

Librium (2,490 reports)

Spinal osteoarthritis treatments and more:

Spinal osteoarthritis (19,799 reports)

How severe was Spinal osteoarthritis and when was it recovered:

Spinal osteoarthritis in Librium

Expand to all the drugs that have ingredients of chlordiazepoxide hydrochloride:

Spinal osteoarthritis and drugs with ingredients of chlordiazepoxide hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,418 drugs)

Browse all the conditions that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,125 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride (the active ingredients of Librium) and Librium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.