Licorice and Thrombocytopenia - a phase IV clinical study of FDA data

Summary:

Thrombocytopenia is reported as a side effect among people who take Licorice (licorice), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cimetidine, and have Local anaesthesia.

The phase IV clinical study analyzes which people have Thrombocytopenia when taking Licorice. It is created by eHealthMe based on reports of 385 people who have side effects when taking Licorice from the FDA, and is updated regularly.

What is Licorice?

Licorice has active ingredients of licorice. eHealthMe is studying from 420 Licorice users. Check the latest studies of Licorice.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 2,793 drugs and 4,869 conditions by eHealthMe. Check the latest studies of Thrombocytopenia.



On Jul, 07, 2026

385 people reported to have side effects when taking Licorice.
Among them, 17 people (4.42%) have Thrombocytopenia.

Could Licorice cause Thrombocytopenia?

Among these 17 people:

How long have people been on Licorice when they have Thrombocytopenia? *

  • < 1 month: 60 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Thrombocytopenia when taking Licorice? *

  • female: 73.33 %
  • male: 26.67 %

What is the age of people who have Thrombocytopenia when taking Licorice? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 14.29 %
  • 60+: 71.43 %

What are other drugs people take besides Licorice? *

  1. Cimetidine: 7 people, 41.18%
  2. Codonopsis: 5 people, 29.41%
  3. Pantoprazole: 5 people, 29.41%
  4. Ephedra: 5 people, 29.41%
  5. Promethazine: 5 people, 29.41%
  6. Rehmannia: 5 people, 29.41%
  7. Fish Oil: 4 people, 23.53%
  8. Prednisone: 3 people, 17.65%
  9. Procardia: 3 people, 17.65%
  10. Sodium Chloride: 3 people, 17.65%

What are other side effects people have besides Thrombocytopenia? *

  1. Fatigue (feeling of tiredness): 3 people, 17.65%
  2. Myelosuppression (a decrease in the production of blood cells): 3 people, 17.65%
  3. Fever: 3 people, 17.65%
  4. Dehydration (dryness resulting from the removal of water): 3 people, 17.65%
  5. Weakness: 3 people, 17.65%
  6. Dyspnea (difficult or laboured breathing): 2 people, 11.76%
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 11.76%
  8. Drowsiness: 2 people, 11.76%
  9. Pneumonia: 2 people, 11.76%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 11.76%

What are the existing conditions these people have? *

  1. Allergies: 5 people, 29.41%
  2. Rashes (redness): 5 people, 29.41%
  3. Platelet Count Increased: 5 people, 29.41%
  4. Ovarian Cancer Stage Iii: 5 people, 29.41%
  5. Nausea And Vomiting: 5 people, 29.41%
  6. Local Anaesthesia: 5 people, 29.41%
  7. Indigestion: 2 people, 11.76%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.76%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 11.76%
  10. H1n1 Influenza (flu (influenza), which is caused by virus influenza a (h1n1)): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Licorice and have Thrombocytopenia?

- Check whether Thrombocytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Licorice:

Thrombocytopenia treatments and more:

How severe was Thrombocytopenia and when was it recovered:

Expand to all the drugs that have ingredients of licorice:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Licorice:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombocytopenia:

Browse all the conditions that are associated with Thrombocytopenia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on licorice (the active ingredients of Licorice) and Licorice (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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