Lidocaine and Macule - a phase IV clinical study of FDA data

Summary:

Macule is reported as a side effect among people who take Lidocaine (lidocaine), especially for people who are female, 50-59 old, also take Cosentyx, and have Psoriasis.

The phase IV clinical study analyzes which people have Macule when taking Lidocaine. It is created by eHealthMe based on reports of 27,239 people who have side effects when taking Lidocaine from the FDA, and is updated regularly.

What is Lidocaine?

Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 27,555 Lidocaine users. Check the latest studies of Lidocaine.

What is Macule?

Macule (a discoloured spot on the skin) is found to be associated with 298 drugs and 706 conditions by eHealthMe. Check the latest studies of Macule.

On Jul, 06, 2026

27,239 people reported to have side effects when taking Lidocaine.
Among them, 11 people (0.04%) have Macule.

Among these 11 people:

What is the gender of people who have Macule when taking Lidocaine? *

female: 80 %
male: 20 %

What is the age of people who have Macule when taking Lidocaine? *

What are other drugs people take besides Lidocaine? *

What are other side effects people have besides Macule? *

Psoriasis (immune-mediated disease that affects the skin): 8 people, 72.73%
Itching: 8 people, 72.73%
Drug Ineffective: 8 people, 72.73%
Papule: 7 people, 63.64%
Rashes (redness): 6 people, 54.55%
Melanocytic Naevus (a type of lesion that contains nevus cells (a type of melanocyte)): 6 people, 54.55%
Dry Skin: 4 people, 36.36%
Joint Pain: 4 people, 36.36%
Skin Exfoliation (removal of the oldest dead skin cells): 4 people, 36.36%
Skin Plaque (red, scaly patches to appear on the skin): 4 people, 36.36%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 8 people, 72.73%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 9.09%
Herpes Zoster: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Lidocaine and have Macule?

- Check whether Macule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lidocaine:

Lidocaine (27,555 reports)

Macule treatments and more:

Macule (3,263 reports)

Browse all side effects of Lidocaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macule:

Macule (298 drugs)

Browse all the conditions that are associated with Macule:

Macule (706 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine (the active ingredients of Lidocaine) and Lidocaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.