Linaclotide and Nausea and vomiting - a phase IV clinical study of FDA data

Summary:

Nausea and vomiting is reported as a side effect among people who take Linaclotide (linaclotide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Constipation.

The phase IV clinical study analyzes which people have Nausea and vomiting when taking Linaclotide. It is created by eHealthMe based on reports of 2,196 people who have side effects when taking Linaclotide from the FDA, and is updated regularly.

What is Linaclotide?

Linaclotide has active ingredients of linaclotide. eHealthMe is studying from 2,197 Linaclotide users. Check the latest studies of Linaclotide.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 3,710 drugs and 5,745 conditions by eHealthMe. Check the latest studies of Nausea and vomiting.

On Jul, 27, 2026

2,196 people reported to have side effects when taking Linaclotide.
Among them, 65 people (2.96%) have Nausea and vomiting.

Could Linaclotide cause Nausea and vomiting?

Among these 65 people:

How long have people been on Linaclotide when they have Nausea and vomiting? *

What is the gender of people who have Nausea and vomiting when taking Linaclotide? *

female: 71.93 %
male: 28.07 %

What is the age of people who have Nausea and vomiting when taking Linaclotide? *

What are other drugs people take besides Linaclotide? *

What are other side effects people have besides Nausea and vomiting? *

Nausea (feeling of having an urge to vomit): 41 people, 63.08%
Headache (pain in head): 23 people, 35.38%
Diarrhea: 22 people, 33.85%
Abdominal Pain: 20 people, 30.77%
Dizziness: 15 people, 23.08%
Pain: 15 people, 23.08%
Drowsiness: 13 people, 20.00%
Constipation: 12 people, 18.46%
Sinusitis (inflammation of sinus): 11 people, 16.92%
High Blood Pressure: 11 people, 16.92%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 21.54%
Constipation: 14 people, 21.54%
Pain: 8 people, 12.31%
Migraine (headache): 8 people, 12.31%
Stress And Anxiety: 8 people, 12.31%
Irritable Bowel Syndrome: 7 people, 10.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.23%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 9.23%
Nausea (feeling of having an urge to vomit): 6 people, 9.23%
Depression: 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Linaclotide and have Nausea and vomiting?

- Check whether Nausea and vomiting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Linaclotide:

Linaclotide (2,197 reports)

Browse all side effects of Linaclotide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea and vomiting:

Nausea and vomiting (3,710 drugs)

Browse all the conditions that are associated with Nausea and vomiting:

Nausea and vomiting (5,745 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linaclotide (the active ingredients of Linaclotide) and Linaclotide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.