Linagliptin and Left ventricular hypertrophy - a phase IV clinical study of FDA data

Summary:

Left ventricular hypertrophy is reported as a side effect among people who take Linagliptin (linagliptin), especially for people who are male, 60+ old, also take Carvedilol, and have Coronary heart disease.

The phase IV clinical study analyzes which people have Left ventricular hypertrophy when taking Linagliptin. It is created by eHealthMe based on reports of 8,096 people who have side effects when taking Linagliptin from the FDA, and is updated regularly.

What is Linagliptin?

Linagliptin has active ingredients of linagliptin. eHealthMe is studying from 8,112 Linagliptin users. Check the latest studies of Linagliptin.

What is Left ventricular hypertrophy?

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart) is found to be associated with 896 drugs and 756 conditions by eHealthMe. Check the latest studies of Left ventricular hypertrophy.

On Jul, 27, 2026

8,096 people reported to have side effects when taking Linagliptin.
Among them, 36 people (0.44%) have Left ventricular hypertrophy.

Could Linagliptin cause Left ventricular hypertrophy?

Among these 36 people:

What is the gender of people who have Left ventricular hypertrophy when taking Linagliptin? *

female: 17.65 %
male: 82.35 %

What is the age of people who have Left ventricular hypertrophy when taking Linagliptin? *

What are other drugs people take besides Linagliptin? *

What are other side effects people have besides Left ventricular hypertrophy? *

Pericardial Effusion (fluid around the heart): 32 people, 88.89%
Weakness: 30 people, 83.33%
Ill-Defined Disorder: 30 people, 83.33%
Hyperlipidaemia (presence of excess lipids in the blood): 30 people, 83.33%
Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 30 people, 83.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 30 people, 83.33%
Fatigue (feeling of tiredness): 30 people, 83.33%
Fainting (loss of consciousness and postural tone): 30 people, 83.33%
Enlarged Heart: 30 people, 83.33%
Electrocardiogram Qt Prolonged: 30 people, 83.33%

What are the existing conditions these people have? *

Coronary Heart Disease (narrowing or blockage of the coronary arteries): 30 people, 83.33%
High Blood Pressure: 29 people, 80.56%
Cardiac Failure: 29 people, 80.56%
Acute Kidney Failure: 29 people, 80.56%
Carotid Arteriosclerosis (plaque deposition in artery): 28 people, 77.78%
Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 19 people, 52.78%
Ill-Defined Disorder: 6 people, 16.67%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 6 people, 16.67%
Left Ventricular Failure (left ventricle fails to contract forcefully): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Linagliptin and have Left ventricular hypertrophy?

- Check whether Left ventricular hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Linagliptin:

Linagliptin (8,112 reports)

Browse all side effects of Linagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (896 drugs)

Browse all the conditions that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (756 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linagliptin (the active ingredients of Linagliptin) and Linagliptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.