Linzess and Rash papular - a phase IV clinical study of FDA data

Summary:

Rash papular is reported as a side effect among people who take Linzess (linaclotide), especially for people who are female, 60+ old, also take Metoclopramide, and have Transitional cell carcinoma.

The phase IV clinical study analyzes which people have Rash papular when taking Linzess. It is created by eHealthMe based on reports of 23,558 people who have side effects when taking Linzess from the FDA, and is updated regularly.

What is Linzess?

Linzess has active ingredients of linaclotide. It is often used in constipation. eHealthMe is studying from 24,086 Linzess users. Check the latest studies of Linzess.

What is Rash papular?

Rash papular (redness with papule) is found to be associated with 1,120 drugs and 1,329 conditions by eHealthMe. Check the latest studies of Rash papular.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

23,558 people reported to have side effects when taking Linzess.
Among them, 20 people (0.08%) have Rash papular.

Among these 20 people:

What is the gender of people who have Rash papular when taking Linzess? *

female: 60 %
male: 40 %

What is the age of people who have Rash papular when taking Linzess? *

What are other drugs people take besides Linzess? *

Oxycontin: 5 people, 25.00%
Sennosides: 5 people, 25.00%
Metoclopramide: 5 people, 25.00%
Wellbutrin: 4 people, 20.00%
Vitamin D3: 3 people, 15.00%
Omeprazole: 3 people, 15.00%
Humira: 3 people, 15.00%
Leflunomide: 2 people, 10.00%
Oxycodone Hydrochloride: 2 people, 10.00%
Otezla: 2 people, 10.00%

What are other side effects people have besides Rash papular? *

Itching: 8 people, 40.00%
Nausea (feeling of having an urge to vomit): 8 people, 40.00%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 25.00%
Delirium (wild excitement): 5 people, 25.00%
Rashes (redness): 4 people, 20.00%
Rash Pruritic (redness with itching): 3 people, 15.00%
Swelling Face: 3 people, 15.00%
Hypersensitivity: 3 people, 15.00%
Rash Erythematous (redness of the skin): 3 people, 15.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.00%

What are the existing conditions these people have? *

Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 5 people, 25.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 10.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.00%
Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 5.00%
Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 1 person, 5.00%
Birth Control: 1 person, 5.00%
Blood Potassium Decreased: 1 person, 5.00%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Linzess and have Rash papular?

- Check whether Rash papular is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Linzess:

Linzess (24,086 reports)

Rash papular treatments and more:

Rash papular (25,753 reports)

Browse all side effects of Linzess:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rash papular:

Rash papular (1,120 drugs)

Browse all the conditions that are associated with Rash papular:

Rash papular (1,329 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linaclotide (the active ingredients of Linzess) and Linzess (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.