Lioresal and Common peroneal nerve dysfunction - a phase IV clinical study of FDA data

Summary:

Common peroneal nerve dysfunction is reported as a side effect among people who take Lioresal (baclofen), especially for people who are female, 50-59 old, also take Ampyra, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Common peroneal nerve dysfunction when taking Lioresal. It is created by eHealthMe based on reports of 20,521 people who have side effects when taking Lioresal from the FDA, and is updated regularly.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 20,572 Lioresal users. Check the latest studies of Lioresal.

What is Common peroneal nerve dysfunction?

Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes) is found to be associated with 651 drugs and 1,130 conditions by eHealthMe. Check the latest studies of Common peroneal nerve dysfunction.

On Aug, 04, 2026

20,521 people reported to have side effects when taking Lioresal.
Among them, 29 people (0.14%) have Common peroneal nerve dysfunction.

Could Lioresal cause Common peroneal nerve dysfunction?

Among these 29 people:

What is the gender of people who have Common peroneal nerve dysfunction when taking Lioresal? *

female: 89.29 %
male: 10.71 %

What is the age of people who have Common peroneal nerve dysfunction when taking Lioresal? *

What are other drugs people take besides Lioresal? *

Ampyra: 7 people, 24.14%
Neurontin: 6 people, 20.69%
Vitamin D3: 6 people, 20.69%
Tylenol: 6 people, 20.69%
Motrin: 5 people, 17.24%
Tecfidera: 5 people, 17.24%
Tobramycin And Dexamethasone: 5 people, 17.24%
Gilenya: 5 people, 17.24%
Aleve: 5 people, 17.24%
Advil: 5 people, 17.24%

What are other side effects people have besides Common peroneal nerve dysfunction? *

Weakness: 17 people, 58.62%
Muscle Spasms (muscle contraction): 12 people, 41.38%
Gait Disturbance: 11 people, 37.93%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 9 people, 31.03%
Stress And Anxiety: 7 people, 24.14%
Mobility Decreased (ability to move is reduced): 7 people, 24.14%
Hypotonia (low muscle tone): 7 people, 24.14%
Feeling Abnormal: 7 people, 24.14%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 20.69%
Muscle Contracture (a permanent shortening of a muscle): 6 people, 20.69%

What are the existing conditions these people have? *

Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 16 people, 55.17%
Gait Disturbance: 11 people, 37.93%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 6.90%
Muscle Spasms (muscle contraction): 2 people, 6.90%
Sleep Disorder: 1 person, 3.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.45%
Neuropathy Peripheral (surface nerve damage): 1 person, 3.45%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 3.45%
Nausea And Vomiting: 1 person, 3.45%
Nausea (feeling of having an urge to vomit): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Common peroneal nerve dysfunction?

- Check whether Common peroneal nerve dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lioresal:

Lioresal (20,572 reports)

Browse all side effects of Lioresal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Common peroneal nerve dysfunction:

Common peroneal nerve dysfunction (651 drugs)

Browse all the conditions that are associated with Common peroneal nerve dysfunction:

Common peroneal nerve dysfunction (1,130 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.