Lioresal and Nerve compression - a phase IV clinical study of FDA data

Summary:

Nerve compression is reported as a side effect among people who take Lioresal (baclofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ditropan, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Nerve compression when taking Lioresal. It is created by eHealthMe based on reports of 20,521 people who have side effects when taking Lioresal from the FDA, and is updated regularly.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 20,572 Lioresal users. Check the latest studies of Lioresal.

What is Nerve compression?

Nerve compression is found to be associated with 799 drugs and 675 conditions by eHealthMe. Check the latest studies of Nerve compression.

On Jul, 29, 2026

20,521 people reported to have side effects when taking Lioresal.
Among them, 34 people (0.17%) have Nerve compression.

Among these 34 people:

How long have people been on Lioresal when they have Nerve compression? *

What is the gender of people who have Nerve compression when taking Lioresal? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Nerve compression when taking Lioresal? *

What are other drugs people take besides Lioresal? *

What are other side effects people have besides Nerve compression? *

Hypoaesthesia (reduced sense of touch or sensation): 11 people, 32.35%
Weakness: 10 people, 29.41%
Oedema Peripheral (superficial swelling): 9 people, 26.47%
Fall: 9 people, 26.47%
Muscle Spasms (muscle contraction): 9 people, 26.47%
Migraine (headache): 8 people, 23.53%
Stable Angina (a constant chest pain): 8 people, 23.53%
Pain: 8 people, 23.53%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 8 people, 23.53%
High Blood Pressure: 8 people, 23.53%

What are the existing conditions these people have? *

Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 12 people, 35.29%
Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 3 people, 8.82%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 8.82%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 8.82%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 3 people, 8.82%
Tumor: 2 people, 5.88%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.88%
Depression: 2 people, 5.88%
Drowsiness: 2 people, 5.88%
Extremity Necrosis (death of body tissue of arms and legs): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Nerve compression?

- Check whether Nerve compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lioresal:

Lioresal (20,572 reports)

Browse all side effects of Lioresal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nerve compression:

Nerve compression (799 drugs)

Browse all the conditions that are associated with Nerve compression:

Nerve compression (675 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.