Lipitor and Macule - a phase IV clinical study of FDA data

Summary:

Macule is reported as a side effect among people who take Lipitor (atorvastatin calcium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Plavix, and have Inflammation.

The phase IV clinical study analyzes which people have Macule when taking Lipitor. It is created by eHealthMe based on reports of 251,142 people who have side effects when taking Lipitor from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,039 Lipitor users. Check the latest studies of Lipitor.

What is Macule?

Macule (a discoloured spot on the skin) is found to be associated with 317 drugs and 697 conditions by eHealthMe. Check the latest studies of Macule.

On Dec, 15, 2025

251,142 people reported to have side effects when taking Lipitor.
Among them, 24 people (0.01%) have Macule.

Among these 24 people:

How long have people been on Lipitor when they have Macule? *

What is the gender of people who have Macule when taking Lipitor? *

female: 50 %
male: 50 %

What is the age of people who have Macule when taking Lipitor? *

What are other drugs people take besides Lipitor? *

What are other side effects people have besides Macule? *

Itching: 7 people, 29.17%
Rashes (redness): 6 people, 25.00%
Dyspnea (difficult or laboured breathing): 5 people, 20.83%
Headache (pain in head): 4 people, 16.67%
Melanocytic Naevus (a type of lesion that contains nevus cells (a type of melanocyte)): 4 people, 16.67%
Gastric Ulcer (stomach ulcer): 4 people, 16.67%
Dry Skin: 4 people, 16.67%
Drug Ineffective: 4 people, 16.67%
Dizziness: 4 people, 16.67%
Osteonecrosis Of Jaw (death of bone of jaw): 4 people, 16.67%

What are the existing conditions these people have? *

Local Swelling (swelling at the site of some application of substance or injury): 2 people, 8.33%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Bipolar Disorder (mood disorder): 2 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.33%
Chest Pain: 2 people, 8.33%
Hypersensitivity: 2 people, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%
Depression: 2 people, 8.33%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.33%
Inflammation: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Lipitor and have Macule?

- Check whether Macule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipitor:

Lipitor (259,039 reports)

Macule treatments and more:

Macule (3,263 reports)

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macule:

Macule (317 drugs)

Browse all the conditions that are associated with Macule:

Macule (697 conditions)

Drugs similar to Lipitor and Macule :

Related publications that referenced our studies

Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium (the active ingredients of Lipitor) and Lipitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.