Lipoic acid and Common peroneal nerve dysfunction - a phase IV clinical study of FDA data

Summary:

Common peroneal nerve dysfunction is reported as a side effect among people who take Lipoic acid (alpha - lipoic acid), especially for people who are male, 60+ old, also take Neurontin, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Common peroneal nerve dysfunction when taking Lipoic acid. It is created by eHealthMe based on reports of 5,562 people who have side effects when taking Lipoic acid from the FDA, and is updated regularly.

What is Lipoic acid?

Lipoic acid has active ingredients of alpha - lipoic acid. It is often used in peripheral neuropathy. eHealthMe is studying from 5,920 Lipoic acid users. Check the latest studies of Lipoic acid.

What is Common peroneal nerve dysfunction?

Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes) is found to be associated with 651 drugs and 1,129 conditions by eHealthMe. Check the latest studies of Common peroneal nerve dysfunction.

On Jul, 21, 2026

5,562 people reported to have side effects when taking Lipoic acid.
Among them, 12 people (0.22%) have Common peroneal nerve dysfunction.

Could Lipoic acid cause Common peroneal nerve dysfunction?

Among these 12 people:

What is the gender of people who have Common peroneal nerve dysfunction when taking Lipoic acid? *

female: 50 %
male: 50 %

What is the age of people who have Common peroneal nerve dysfunction when taking Lipoic acid? *

What are other drugs people take besides Lipoic acid? *

What are other side effects people have besides Common peroneal nerve dysfunction? *

Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 8 people, 66.67%
Neuropathy Peripheral (surface nerve damage): 8 people, 66.67%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 50.00%
Fatigue (feeling of tiredness): 6 people, 50.00%
Pain In Extremity: 5 people, 41.67%
Rashes (redness): 5 people, 41.67%
Stress And Anxiety: 5 people, 41.67%
Gait Disturbance: 5 people, 41.67%
Joint Pain: 5 people, 41.67%
Dry Eyes (lack of adequate tears): 4 people, 33.33%

What are the existing conditions these people have? *

High Blood Cholesterol: 5 people, 41.67%
Depression: 4 people, 33.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
Sinus Disorder (disease of sinus): 3 people, 25.00%
Dermatitis Herpetiformis (chronic blistering skin condition, characterized by blisters filled with a watery fluid): 3 people, 25.00%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 3 people, 25.00%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 3 people, 25.00%
Sleep Disorder: 3 people, 25.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lipoic acid and have Common peroneal nerve dysfunction?

- Check whether Common peroneal nerve dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipoic acid:

Lipoic acid (5,920 reports)

Browse all side effects of Lipoic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Common peroneal nerve dysfunction:

Common peroneal nerve dysfunction (651 drugs)

Browse all the conditions that are associated with Common peroneal nerve dysfunction:

Common peroneal nerve dysfunction (1,129 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alpha - lipoic acid (the active ingredients of Lipoic acid) and Lipoic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.