Lisinopril and hydrochlorothiazide and Ocular hyperaemia - a phase IV clinical study of FDA data

Summary:

Ocular hyperaemia is reported as a side effect among people who take Lisinopril and hydrochlorothiazide (hydrochlorothiazide; lisinopril), especially for people who are female, 60+ old, also take Dupixent, and have Neurotrophic keratopathy.

The phase IV clinical study analyzes which people have Ocular hyperaemia when taking Lisinopril and hydrochlorothiazide. It is created by eHealthMe based on reports of 8,870 people who have side effects when taking Lisinopril and hydrochlorothiazide from the FDA, and is updated regularly.

What is Lisinopril and hydrochlorothiazide?

Lisinopril and hydrochlorothiazide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 10,259 Lisinopril and hydrochlorothiazide users. Check the latest studies of Lisinopril and hydrochlorothiazide.

What is Ocular hyperaemia?

Ocular hyperaemia (an abnormally large amount of blood in eye) is found to be associated with 1,357 drugs and 1,499 conditions by eHealthMe. Check the latest studies of Ocular hyperaemia.



On Jul, 04, 2026

8,870 people reported to have side effects when taking Lisinopril and hydrochlorothiazide.
Among them, 28 people (0.32%) have Ocular hyperaemia.

Could Lisinopril and hydrochlorothiazide cause Ocular hyperaemia?

Among these 28 people:

What is the gender of people who have Ocular hyperaemia when taking Lisinopril and hydrochlorothiazide? *

  • female: 74.07 %
  • male: 25.93 %

What is the age of people who have Ocular hyperaemia when taking Lisinopril and hydrochlorothiazide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.76 %
  • 50-59: 33.33 %
  • 60+: 61.9 %

What are other drugs people take besides Lisinopril and hydrochlorothiazide? *

  1. Dupixent: 6 people, 21.43%
  2. Oxervate: 5 people, 17.86%
  3. Aspirin: 4 people, 14.29%
  4. Diazepam: 4 people, 14.29%
  5. Zyrtec: 3 people, 10.71%
  6. Metformin: 3 people, 10.71%
  7. Reclast: 3 people, 10.71%
  8. Restasis: 3 people, 10.71%
  9. Atenolol: 3 people, 10.71%
  10. Atorvastatin Calcium: 3 people, 10.71%

What are other side effects people have besides Ocular hyperaemia? *

  1. Eye Pain: 6 people, 21.43%
  2. Headache (pain in head): 6 people, 21.43%
  3. Eye Swelling: 5 people, 17.86%
  4. Vision Blurred: 5 people, 17.86%
  5. Eye Irritation: 5 people, 17.86%
  6. Nausea (feeling of having an urge to vomit): 5 people, 17.86%
  7. Eye Pruritus (eye itching): 5 people, 17.86%
  8. Conjunctivitis (pink eye): 4 people, 14.29%
  9. Swelling Face: 4 people, 14.29%
  10. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 10.71%

What are the existing conditions these people have? *

  1. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 5 people, 17.86%
  2. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 10.71%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.14%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.14%
  5. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 7.14%
  6. Ulcerative Keratitis (ulcerative inflammation of the cornea): 1 person, 3.57%
  7. Eosinophilic Esophagitis (Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell): 1 person, 3.57%
  8. Asthma: 1 person, 3.57%
  9. Dry Eyes (lack of adequate tears): 1 person, 3.57%
  10. Herpes Zoster: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and hydrochlorothiazide and have Ocular hyperaemia?

- Check whether Ocular hyperaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril and hydrochlorothiazide:

Ocular hyperaemia treatments and more:

How severe was Ocular hyperaemia and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide; lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril and hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ocular hyperaemia:

Browse all the conditions that are associated with Ocular hyperaemia:


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; lisinopril (the active ingredients of Lisinopril and hydrochlorothiazide) and Lisinopril and hydrochlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: