Listerine and Overdose - a phase IV clinical study of FDA data

Summary:

Overdose is reported as a side effect among people who take Listerine (menthol, thymol, methyl salicylate, eucalyptol), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Acetaminophen, and have Accidental exposure.

The phase IV clinical study analyzes which people have Overdose when taking Listerine. It is created by eHealthMe based on reports of 1,150 people who have side effects when taking Listerine from the FDA, and is updated regularly.

What is Listerine?

Listerine has active ingredients of menthol, thymol, methyl salicylate, eucalyptol. eHealthMe is studying from 1,164 Listerine users. Check the latest studies of Listerine.

What is Overdose?

Overdose is found to be associated with 2,211 drugs and 2,475 conditions by eHealthMe. Check the latest studies of Overdose.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

1,150 people reported to have side effects when taking Listerine.
Among them, 20 people (1.74%) have Overdose.

Among these 20 people:

How long have people been on Listerine when they have Overdose? *

What is the gender of people who have Overdose when taking Listerine? *

female: 50 %
male: 50 %

What is the age of people who have Overdose when taking Listerine? *

What are other drugs people take besides Listerine? *

What are other side effects people have besides Overdose? *

Abdominal Pain: 2 people, 10.00%
Drowsiness: 2 people, 10.00%
Adverse Drug Reaction: 2 people, 10.00%
Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 2 people, 10.00%
Anion Gap Abnormal: 2 people, 10.00%
Nausea And Vomiting: 2 people, 10.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.00%
Heart Attack: 2 people, 10.00%
Blood Ethanol Increased: 2 people, 10.00%
White Blood Cell Count Increased: 1 person, 5.00%

What are the existing conditions these people have? *

High Blood Pressure: 1 person, 5.00%
Euphoric Mood (excessively happy but may become angry or irritable): 1 person, 5.00%
Birth Control: 1 person, 5.00%
Alcoholism (problems with alcohol): 1 person, 5.00%
Accidental Exposure: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Listerine and have Overdose?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Listerine:

Listerine (1,164 reports)

Overdose treatments and more:

Overdose (229,245 reports)

How severe was Overdose and when was it recovered:

Overdose in Listerine

Expand to all the drugs that have ingredients of menthol, thymol, methyl salicylate, eucalyptol:

Overdose and drugs with ingredients of menthol, thymol, methyl salicylate, eucalyptol

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Listerine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overdose:

Overdose (2,211 drugs)

Browse all the conditions that are associated with Overdose:

Overdose (2,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on menthol, thymol, methyl salicylate, eucalyptol (the active ingredients of Listerine) and Listerine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.