Lo/ovral and Wax blockage - a phase IV clinical study of FDA data

Summary:

Wax blockage is reported as a side effect among people who take Lo/ovral (ethinyl estradiol; norgestrel), especially for people who are female, 30-39 old, also take Azithromycin, and have Eczema.

The phase IV clinical study analyzes which people have Wax blockage when taking Lo/ovral. It is created by eHealthMe based on reports of 1,243 people who have side effects when taking Lo/ovral from the FDA, and is updated regularly.

What is Lo/ovral?

Lo/ovral has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 1,298 Lo/ovral users. Check the latest studies of Lo/ovral.

What is Wax blockage?

Wax blockage is found to be associated with 409 drugs and 973 conditions by eHealthMe. Check the latest studies of Wax blockage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 09, 2026

1,243 people reported to have side effects when taking Lo/ovral.
Among them, 12 people (0.97%) have Wax blockage.

Among these 12 people:

What is the gender of people who have Wax blockage when taking Lo/ovral? *

female: 100 %
male: 0.0 %

What is the age of people who have Wax blockage when taking Lo/ovral? *

What are other drugs people take besides Lo/ovral? *

What are other side effects people have besides Wax blockage? *

Weight Loss: 12 people, 100.00%
Fall: 12 people, 100.00%
Joint Swelling: 12 people, 100.00%
Joint Range Of Motion Decreased (disease of joint movement): 12 people, 100.00%
Joint Pain: 12 people, 100.00%
High Blood Pressure: 12 people, 100.00%
High Blood Cholesterol: 12 people, 100.00%
Head Injury: 12 people, 100.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 12 people, 100.00%
Genital Herpes (herpes infection of genital): 12 people, 100.00%

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 12 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lo/ovral and have Wax blockage?

- Check whether Wax blockage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lo/ovral:

Lo/ovral (1,298 reports)

Wax blockage treatments and more:

Wax blockage (1,960 reports)

Browse all side effects of Lo/ovral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wax blockage:

Wax blockage (409 drugs)

Browse all the conditions that are associated with Wax blockage:

Wax blockage (973 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestrel (the active ingredients of Lo/ovral) and Lo/ovral (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.