Lodine and Haemorrhoids - a phase IV clinical study of FDA data

Summary:

Haemorrhoids is reported as a side effect among people who take Lodine (etodolac), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Vicodin, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Haemorrhoids when taking Lodine. It is created by eHealthMe based on reports of 3,671 people who have side effects when taking Lodine from the FDA, and is updated regularly.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

What is Haemorrhoids?

Haemorrhoids (a swollen vein or group of veins in the region of the anus) is found to be associated with 1,546 drugs and 1,391 conditions by eHealthMe. Check the latest studies of Haemorrhoids.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

3,671 people reported to have side effects when taking Lodine.
Among them, 54 people (1.47%) have Haemorrhoids.

Among these 54 people:

How long have people been on Lodine when they have Haemorrhoids? *

What is the gender of people who have Haemorrhoids when taking Lodine? *

female: 76.19 %
male: 23.81 %

What is the age of people who have Haemorrhoids when taking Lodine? *

What are other drugs people take besides Lodine? *

What are other side effects people have besides Haemorrhoids? *

Stress And Anxiety: 44 people, 81.48%
Depression: 38 people, 70.37%
Emotional Distress: 35 people, 64.81%
Osteomyelitis (infection of bone): 33 people, 61.11%
Deformity (disfigurement): 33 people, 61.11%
Rashes (redness): 32 people, 59.26%
Hypoaesthesia (reduced sense of touch or sensation): 29 people, 53.70%
Diarrhea: 29 people, 53.70%
Joint Pain: 29 people, 53.70%
Fatigue (feeling of tiredness): 29 people, 53.70%

What are the existing conditions these people have? *

Stress And Anxiety: 19 people, 35.19%
Breast Cancer: 14 people, 25.93%
Bone Pain: 12 people, 22.22%
Vitamin E Deficiency: 2 people, 3.70%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 3.70%
High Blood Pressure: 2 people, 3.70%
Osteoporosis (bones weak and more likely to break): 1 person, 1.85%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 1.85%
Breast Cancer Metastatic: 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lodine and have Haemorrhoids?

- Check whether Haemorrhoids is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lodine:

Lodine (3,846 reports)

Haemorrhoids treatments and more:

Haemorrhoids (32,936 reports)

Browse all side effects of Lodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemorrhoids:

Haemorrhoids (1,546 drugs)

Browse all the conditions that are associated with Haemorrhoids:

Haemorrhoids (1,391 conditions)

Related publications that referenced our studies

Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .
Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on etodolac (the active ingredients of Lodine) and Lodine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.