Lodine and Hernia - a phase IV clinical study of FDA data

Summary:

Hernia is reported as a side effect among people who take Lodine (etodolac), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Flexeril, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Hernia when taking Lodine. It is created by eHealthMe based on reports of 3,671 people who have side effects when taking Lodine from the FDA, and is updated regularly.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

What is Hernia?

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle) is found to be associated with 1,302 drugs and 1,499 conditions by eHealthMe. Check the latest studies of Hernia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

3,671 people reported to have side effects when taking Lodine.
Among them, 15 people (0.41%) have Hernia.

Among these 15 people:

How long have people been on Lodine when they have Hernia? *

What is the gender of people who have Hernia when taking Lodine? *

female: 60 %
male: 40 %

What is the age of people who have Hernia when taking Lodine? *

What are other drugs people take besides Lodine? *

What are other side effects people have besides Hernia? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 46.67%
Intervertebral Disc Protrusion (spinal disc protrusion): 7 people, 46.67%
Anaemia (lack of blood): 7 people, 46.67%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 6 people, 40.00%
Scoliosis (a medical condition in which a person's spine is curved from side to side): 6 people, 40.00%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 40.00%
Spinal Column Stenosis (narrowing of spinal column): 6 people, 40.00%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 40.00%
Stress And Anxiety: 6 people, 40.00%
Osteonecrosis Of Jaw (death of bone of jaw): 6 people, 40.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 26.67%
Multiple Myeloma (cancer of the plasma cells): 4 people, 26.67%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 20.00%
Headache (pain in head): 3 people, 20.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 13.33%
Urination - Excessive At Night: 1 person, 6.67%
Urinary Tract Disorder: 1 person, 6.67%
Nausea And Vomiting: 1 person, 6.67%
Nausea (feeling of having an urge to vomit): 1 person, 6.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lodine and have Hernia?

- Check whether Hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lodine:

Lodine (3,846 reports)

Hernia treatments and more:

Hernia (31,430 reports)

Browse all side effects of Lodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hernia:

Hernia (1,302 drugs)

Browse all the conditions that are associated with Hernia:

Hernia (1,499 conditions)

Related publications that referenced our studies

Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .
Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on etodolac (the active ingredients of Lodine) and Lodine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.