Lodine and Hypersensitivity - a phase IV clinical study of FDA data

Summary:

Hypersensitivity is reported as a side effect among people who take Lodine (etodolac), especially for people who are female, 60+ old, also take Lipitor, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Hypersensitivity when taking Lodine. It is created by eHealthMe based on reports of 3,671 people who have side effects when taking Lodine from the FDA, and is updated regularly.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

What is Hypersensitivity?

Hypersensitivity is found to be associated with 2,750 drugs and 2,915 conditions by eHealthMe. Check the latest studies of Hypersensitivity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

3,671 people reported to have side effects when taking Lodine.
Among them, 49 people (1.33%) have Hypersensitivity.

Among these 49 people:

What is the gender of people who have Hypersensitivity when taking Lodine? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Hypersensitivity when taking Lodine? *

What are other drugs people take besides Lodine? *

What are other side effects people have besides Hypersensitivity? *

Face Oedema (swelling of face): 7 people, 14.29%
Nausea (feeling of having an urge to vomit): 6 people, 12.24%
Itching: 6 people, 12.24%
Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 10.20%
Angioneurotic Oedema (swelling that occurs just beneath the surface of the skin or mucous membranes): 5 people, 10.20%
Nausea And Vomiting: 3 people, 6.12%
Heart Attack: 3 people, 6.12%
Pain In Extremity: 3 people, 6.12%
Skin Blushing/flushing (a sudden reddening of the face, neck): 3 people, 6.12%
International Normalised Ratio Decreased: 2 people, 4.08%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.12%
High Blood Pressure: 2 people, 4.08%
High Blood Cholesterol: 2 people, 4.08%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 4.08%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 4.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.04%
Heart Disease: 1 person, 2.04%
Headache (pain in head): 1 person, 2.04%
Gastrointestinal Pain: 1 person, 2.04%
Thyroid Diseases: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Lodine and have Hypersensitivity?

- Check whether Hypersensitivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lodine:

Lodine (3,846 reports)

Hypersensitivity treatments and more:

Hypersensitivity (272,618 reports)

Browse all side effects of Lodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypersensitivity:

Hypersensitivity (2,750 drugs)

Browse all the conditions that are associated with Hypersensitivity:

Hypersensitivity (2,915 conditions)

Related publications that referenced our studies

Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .
Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on etodolac (the active ingredients of Lodine) and Lodine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.