Lokelma and Dyspnea exacerbated - a phase IV clinical study of FDA data

Summary:

Dyspnea exacerbated is reported as a side effect among people who take Lokelma (sodium zirconium cyclosilicate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sodium Bicarbonate, and have Hyperkalemia.

The phase IV clinical study analyzes which people have Dyspnea exacerbated when taking Lokelma. It is created by eHealthMe based on reports of 1,675 people who have side effects when taking Lokelma from the FDA, and is updated regularly.

What is Lokelma?

Lokelma has active ingredients of sodium zirconium cyclosilicate. eHealthMe is studying from 1,678 Lokelma users. Check the latest studies of Lokelma.

What is Dyspnea exacerbated?

Dyspnea exacerbated is found to be associated with 3,314 drugs and 1,659 conditions by eHealthMe. Check the latest studies of Dyspnea exacerbated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

1,675 people reported to have side effects when taking Lokelma.
Among them, 33 people (1.97%) have Dyspnea exacerbated.

Could Lokelma cause Dyspnea exacerbated?

Among these 33 people:

How long have people been on Lokelma when they have Dyspnea exacerbated? *

What is the gender of people who have Dyspnea exacerbated when taking Lokelma? *

female: 43.33 %
male: 56.67 %

What is the age of people who have Dyspnea exacerbated when taking Lokelma? *

What are other drugs people take besides Lokelma? *

What are other side effects people have besides Dyspnea exacerbated? *

Weakness: 7 people, 21.21%
Hyperkalemia (damage to or disease of the kidney): 7 people, 21.21%
Fatigue (feeling of tiredness): 5 people, 15.15%
Peripheral Swelling: 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Nausea (feeling of having an urge to vomit): 4 people, 12.12%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.12%
Chest Pain: 4 people, 12.12%
Weight Increased: 3 people, 9.09%
Itching: 3 people, 9.09%

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 12 people, 36.36%
Renal Cell Carcinoma (a kidney cancer): 2 people, 6.06%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 6.06%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 6.06%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.06%
Cardiac Failure Chronic: 2 people, 6.06%
Cardiomyopathy (weakening of the heart muscle): 2 people, 6.06%
Hiv Infection: 2 people, 6.06%
Cystic Fibrosis (disease of the secretary glands): 2 people, 6.06%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Lokelma and have Dyspnea exacerbated?

- Check whether Dyspnea exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lokelma:

Lokelma (1,678 reports)

Dyspnea exacerbated treatments and more:

Dyspnea exacerbated (2,061 reports)

How severe was Dyspnea exacerbated and when was it recovered:

Dyspnea exacerbated in Lokelma

Expand to all the drugs that have ingredients of sodium zirconium cyclosilicate:

Dyspnea exacerbated and drugs with ingredients of sodium zirconium cyclosilicate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lokelma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dyspnea exacerbated:

Dyspnea exacerbated (3,314 drugs)

Browse all the conditions that are associated with Dyspnea exacerbated:

Dyspnea exacerbated (1,659 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sodium zirconium cyclosilicate (the active ingredients of Lokelma) and Lokelma (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.