Lomotil and Neoplasm progression - a phase IV clinical study of FDA data

Summary:

Neoplasm progression is reported as a side effect among people who take Lomotil (atropine sulfate; diphenoxylate hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Nausea.

The phase IV clinical study analyzes which people have Neoplasm progression when taking Lomotil. It is created by eHealthMe based on reports of 18,891 people who have side effects when taking Lomotil from the FDA, and is updated regularly.

What is Lomotil?

Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.

What is Neoplasm progression?

Neoplasm progression (growth of tumour) is found to be associated with 1,067 drugs and 915 conditions by eHealthMe. Check the latest studies of Neoplasm progression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

18,891 people reported to have side effects when taking Lomotil.
Among them, 74 people (0.39%) have Neoplasm progression.

Could Lomotil cause Neoplasm progression?

Among these 74 people:

How long have people been on Lomotil when they have Neoplasm progression? *

What is the gender of people who have Neoplasm progression when taking Lomotil? *

female: 58.21 %
male: 41.79 %

What is the age of people who have Neoplasm progression when taking Lomotil? *

What are other drugs people take besides Lomotil? *

What are other side effects people have besides Neoplasm progression? *

Fatigue (feeling of tiredness): 26 people, 35.14%
Weakness: 21 people, 28.38%
Nausea (feeling of having an urge to vomit): 19 people, 25.68%
High Blood Pressure: 12 people, 16.22%
Pain: 12 people, 16.22%
Thrombocytopenia (decrease of platelets in blood): 11 people, 14.86%
Nausea And Vomiting: 11 people, 14.86%
Constipation: 11 people, 14.86%
Abdominal Pain: 10 people, 13.51%
Dyspnea (difficult or laboured breathing): 10 people, 13.51%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 13 people, 17.57%
Pain: 10 people, 13.51%
Gastrointestinal Stromal Tumor: 8 people, 10.81%
Nausea And Vomiting: 7 people, 9.46%
High Blood Cholesterol: 6 people, 8.11%
High Blood Pressure: 6 people, 8.11%
Breast Cancer Female: 6 people, 8.11%
Multiple Myeloma (cancer of the plasma cells): 6 people, 8.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.76%
Renal Cell Carcinoma (a kidney cancer): 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

Do you take Lomotil and have Neoplasm progression?

- Check whether Neoplasm progression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lomotil:

Lomotil (19,184 reports)

Neoplasm progression treatments and more:

Neoplasm progression (41,778 reports)

How severe was Neoplasm progression and when was it recovered:

Neoplasm progression in Lomotil

Expand to all the drugs that have ingredients of atropine sulfate; diphenoxylate hydrochloride:

Neoplasm progression and drugs with ingredients of atropine sulfate; diphenoxylate hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neoplasm progression:

Neoplasm progression (1,067 drugs)

Browse all the conditions that are associated with Neoplasm progression:

Neoplasm progression (915 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on atropine sulfate; diphenoxylate hydrochloride (the active ingredients of Lomotil) and Lomotil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.