Loperamide hydrochloride and Synovitis - a phase IV clinical study of FDA data

Summary:

Synovitis is reported as a side effect among people who take Loperamide hydrochloride (loperamide hydrochloride), especially for people who are female, 60+ old, also take Dilaudid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Synovitis when taking Loperamide hydrochloride. It is created by eHealthMe based on reports of 10,478 people who have side effects when taking Loperamide hydrochloride from the FDA, and is updated regularly.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

What is Synovitis?

Synovitis (inflammation of the synovial membrane) is found to be associated with 694 drugs and 508 conditions by eHealthMe. Check the latest studies of Synovitis.

On Jul, 04, 2026

10,478 people reported to have side effects when taking Loperamide hydrochloride.
Among them, 24 people (0.23%) have Synovitis.

Could Loperamide hydrochloride cause Synovitis?

Among these 24 people:

What is the gender of people who have Synovitis when taking Loperamide hydrochloride? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Synovitis when taking Loperamide hydrochloride? *

What are other drugs people take besides Loperamide hydrochloride? *

What are other side effects people have besides Synovitis? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 24 people, 100.00%
Joint Pain: 22 people, 91.67%
Drug Ineffective: 20 people, 83.33%
Peripheral Swelling: 20 people, 83.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 20 people, 83.33%
Drug Intolerance (drug sensitivity): 20 people, 83.33%
Joint Swelling: 20 people, 83.33%
Infection: 18 people, 75.00%
High Blood Cholesterol: 18 people, 75.00%
Tenderness (pain or discomfort when an affected area is touched): 18 people, 75.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 20 people, 83.33%
Pain: 9 people, 37.50%
Joint Pain: 3 people, 12.50%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Loperamide hydrochloride and have Synovitis?

- Check whether Synovitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loperamide hydrochloride:

Loperamide hydrochloride (10,814 reports)

Synovitis treatments and more:

Synovitis (24,130 reports)

Browse all side effects of Loperamide hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovitis:

Synovitis (694 drugs)

Browse all the conditions that are associated with Synovitis:

Synovitis (508 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Loperamide hydrochloride) and Loperamide hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.