Lopid and Intervertebral disc herniation - a phase IV clinical study of FDA data

Summary:

Intervertebral disc herniation is reported as a side effect among people who take Lopid (gemfibrozil), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Glipizide, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Intervertebral disc herniation when taking Lopid. It is created by eHealthMe based on reports of 9,538 people who have side effects when taking Lopid from the FDA, and is updated regularly.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

What is Intervertebral disc herniation?

Intervertebral disc herniation (spinal disc herniation) is found to be associated with 34 drugs and 64 conditions by eHealthMe. Check the latest studies of Intervertebral disc herniation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

9,538 people reported to have side effects when taking Lopid.
Among them, 20 people (0.21%) have Intervertebral disc herniation.

Could Lopid cause Intervertebral disc herniation?

Among these 20 people:

How long have people been on Lopid when they have Intervertebral disc herniation? *

What is the gender of people who have Intervertebral disc herniation when taking Lopid? *

female: 30 %
male: 70 %

What is the age of people who have Intervertebral disc herniation when taking Lopid? *

What are other drugs people take besides Lopid? *

Glipizide: 10 people, 50.00%
Isosorbide Mononitrate: 6 people, 30.00%
Gabapentin: 6 people, 30.00%
Simvastatin: 6 people, 30.00%
Alprazolam: 5 people, 25.00%
Cimetidine: 5 people, 25.00%
Omeprazole: 5 people, 25.00%
Fosinopril Sodium: 5 people, 25.00%
Famotidine: 5 people, 25.00%
Nitroglycerin: 5 people, 25.00%

What are other side effects people have besides Intervertebral disc herniation? *

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 12 people, 60.00%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 40.00%
Blood Glucose Increased: 7 people, 35.00%
Spinal Osteoarthritis (joint cartilage loss in spine): 7 people, 35.00%
Drug Ineffective: 6 people, 30.00%
Enlarged Prostate: 6 people, 30.00%
Carotid Artery Stenosis (narrowing of carotid artery): 6 people, 30.00%
Haematuria (presence of blood in urine): 5 people, 25.00%
Back Pain: 5 people, 25.00%
Vision Blurred: 5 people, 25.00%

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lopid and have Intervertebral disc herniation?

- Check whether Intervertebral disc herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopid:

Lopid (9,700 reports)

Browse all side effects of Lopid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc herniation:

Intervertebral disc herniation (34 drugs)

Browse all the conditions that are associated with Intervertebral disc herniation:

Intervertebral disc herniation (64 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil (the active ingredients of Lopid) and Lopid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.