Lopressor and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is reported as a side effect among people who take Lopressor (metoprolol tartrate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Clonidine, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hypertensive crisis when taking Lopressor. It is created by eHealthMe based on reports of 32,072 people who have side effects when taking Lopressor from the FDA, and is updated regularly.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 786 drugs and 932 conditions by eHealthMe. Check the latest studies of Hypertensive crisis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

32,072 people reported to have side effects when taking Lopressor.
Among them, 68 people (0.21%) have Hypertensive crisis.

Could Lopressor cause Hypertensive crisis?

Among these 68 people:

How long have people been on Lopressor when they have Hypertensive crisis? *

What is the gender of people who have Hypertensive crisis when taking Lopressor? *

female: 75.76 %
male: 24.24 %

What is the age of people who have Hypertensive crisis when taking Lopressor? *

What are other drugs people take besides Lopressor? *

What are other side effects people have besides Hypertensive crisis? *

Dyspnea (difficult or laboured breathing): 21 people, 30.88%
Headache (pain in head): 21 people, 30.88%
Nausea (feeling of having an urge to vomit): 20 people, 29.41%
Cough: 18 people, 26.47%
Pneumonia: 17 people, 25.00%
Chest Pain: 16 people, 23.53%
Dizziness: 15 people, 22.06%
Cardiac Failure Congestive: 14 people, 20.59%
Drug Ineffective: 14 people, 20.59%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 20.59%

What are the existing conditions these people have? *

Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 8.82%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 8.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.35%
Stress And Anxiety: 4 people, 5.88%
Blood Pressure Abnormal: 4 people, 5.88%
Blood Pressure Systolic Increased: 4 people, 5.88%
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 3 people, 4.41%
Pain: 2 people, 2.94%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 2.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Lopressor and have Hypertensive crisis?

- Check whether Hypertensive crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopressor:

Lopressor (33,152 reports)

Browse all side effects of Lopressor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive crisis:

Hypertensive crisis (786 drugs)

Browse all the conditions that are associated with Hypertensive crisis:

Hypertensive crisis (932 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoprolol tartrate (the active ingredients of Lopressor) and Lopressor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.