Lopurin and Dermo-hypodermitis - a phase IV clinical study of FDA data

Summary:

Dermo-hypodermitis is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Dermo-hypodermitis when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Dermo-hypodermitis?

Dermo-hypodermitis (skin and subcutaneous tissue bacterial infections) is found to be associated with 50 drugs and 127 conditions by eHealthMe. Check the latest studies of Dermo-hypodermitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 11 people (0.01%) have Dermo-hypodermitis.

Among these 11 people:

What is the gender of people who have Dermo-hypodermitis when taking Lopurin? *

female: 20 %
male: 80 %

What is the age of people who have Dermo-hypodermitis when taking Lopurin? *

What are other drugs people take besides Lopurin? *

Amlodipine: 6 people, 54.55%
Heparin: 4 people, 36.36%
Acetylsalicylic Acid: 3 people, 27.27%
Kayexalate: 3 people, 27.27%
Clopidogrel: 3 people, 27.27%
Furosemide: 3 people, 27.27%
Tamsulosin Hydrochloride: 3 people, 27.27%
Calciparine: 2 people, 18.18%
Eliquis: 2 people, 18.18%
Januvia: 2 people, 18.18%

What are other side effects people have besides Dermo-hypodermitis? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 54.55%
Fever: 5 people, 45.45%
Fall: 5 people, 45.45%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 4 people, 36.36%
Pain In Extremity: 3 people, 27.27%
Inflammation: 3 people, 27.27%
Cardiac Failure: 2 people, 18.18%
Muscle Aches (muscle pain): 2 people, 18.18%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 9.09%
Colitis Ischaemic (due to infection of intestine impaired blood supply to colon): 1 person, 9.09%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 45.45%
Cardiac Failure: 3 people, 27.27%
Enlarged Prostate: 3 people, 27.27%
High Blood Cholesterol: 2 people, 18.18%
Type 2 Diabetes: 2 people, 18.18%
Oedema (fluid collection in tissue): 1 person, 9.09%
Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum): 1 person, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
Back Pain: 1 person, 9.09%
Bronchopneumopathy: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Dermo-hypodermitis?

- Check whether Dermo-hypodermitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dermo-hypodermitis:

Dermo-hypodermitis (50 drugs)

Browse all the conditions that are associated with Dermo-hypodermitis:

Dermo-hypodermitis (127 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.