Lopurin and Joint warmth - a phase IV clinical study of FDA data

Summary:

Joint warmth is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, also take Metformin, and have Diabetes.

The phase IV clinical study analyzes which people have Joint warmth when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Joint warmth?

Joint warmth is found to be associated with 165 drugs and 250 conditions by eHealthMe. Check the latest studies of Joint warmth.

On Jul, 31, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 13 people (0.01%) have Joint warmth.

Among these 13 people:

What is the gender of people who have Joint warmth when taking Lopurin? *

female: 7.69 %
male: 92.31 %

What is the age of people who have Joint warmth when taking Lopurin? *

What are other drugs people take besides Lopurin? *

What are other side effects people have besides Joint warmth? *

Joint Swelling: 4 people, 30.77%
Cough: 4 people, 30.77%
Blood Bilirubin Increased: 4 people, 30.77%
Pain In Extremity: 4 people, 30.77%
Arrhythmias (irregular heartbeat): 4 people, 30.77%
Rashes (redness): 4 people, 30.77%
Cellulitis (infection under the skin): 3 people, 23.08%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 23.08%
Joint Pain: 3 people, 23.08%
Hyperkeratosis (thickening of the outer layer of the skin): 3 people, 23.08%

What are the existing conditions these people have? *

Diabetes: 4 people, 30.77%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 23.08%
High Blood Pressure: 2 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 15.38%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 15.38%
Thyroid Diseases: 1 person, 7.69%
Arthritis Fungal (inflammation of a joint by a fungus): 1 person, 7.69%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.69%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Joint warmth?

- Check whether Joint warmth is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Joint warmth treatments and more:

Joint warmth (1,479 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint warmth:

Joint warmth (165 drugs)

Browse all the conditions that are associated with Joint warmth:

Joint warmth (250 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.