Lopurin and Muscle function loss - a phase IV clinical study of FDA data

Summary:

Muscle function loss is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Simvastatin, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Muscle function loss when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,797 Lopurin users. Check the latest studies of Lopurin.

What is Muscle function loss?

Muscle function loss is found to be associated with 1,001 drugs and 1,521 conditions by eHealthMe. Check the latest studies of Muscle function loss.

On Jul, 05, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 127 people (0.07%) have Muscle function loss.

Could Lopurin cause Muscle function loss?

Among these 127 people:

How long have people been on Lopurin when they have Muscle function loss? *

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What is the gender of people who have Muscle function loss when taking Lopurin? *

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* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Muscle function loss?

- Check whether Muscle function loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,797 reports)

Muscle function loss treatments and more:

Muscle function loss (17,723 reports)

How severe was Muscle function loss and when was it recovered:

Muscle function loss in Lopurin

Expand to all the drugs that have ingredients of allopurinol:

Muscle function loss and drugs with ingredients of allopurinol (131 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle function loss:

Muscle function loss (1,001 drugs)

Browse all the conditions that are associated with Muscle function loss:

Muscle function loss (1,521 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.