Lopurin and Surgical failure - a phase IV clinical study of FDA data

Summary:

Surgical failure is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Surgical failure when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Surgical failure?

Surgical failure is found to be associated with 140 drugs and 256 conditions by eHealthMe. Check the latest studies of Surgical failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 13 people (0.01%) have Surgical failure.

Among these 13 people:

What is the gender of people who have Surgical failure when taking Lopurin? *

female: 38.46 %
male: 61.54 %

What is the age of people who have Surgical failure when taking Lopurin? *

What are other drugs people take besides Lopurin? *

Ambien: 4 people, 30.77%
Aspirin: 4 people, 30.77%
Zoloft: 3 people, 23.08%
Ditropan Xl: 3 people, 23.08%
Flutamide: 3 people, 23.08%
Ondansetron: 3 people, 23.08%
Cephalexin: 3 people, 23.08%
Norvasc: 3 people, 23.08%
Chlorhexidine Gluconate: 3 people, 23.08%
Clonidine: 3 people, 23.08%

What are other side effects people have besides Surgical failure? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 5 people, 38.46%
Weight Decreased: 4 people, 30.77%
Sinusitis (inflammation of sinus): 4 people, 30.77%
Anaemia (lack of blood): 4 people, 30.77%
Depression: 4 people, 30.77%
Diarrhea: 4 people, 30.77%
Enlarged Heart: 4 people, 30.77%
Weakness: 4 people, 30.77%
Joint Pain: 4 people, 30.77%
Nausea (feeling of having an urge to vomit): 4 people, 30.77%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 30.77%
Multiple Myeloma (cancer of the plasma cells): 3 people, 23.08%
Light Chain Analysis Increased: 3 people, 23.08%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 15.38%
Diabetes: 2 people, 15.38%
High Blood Cholesterol: 2 people, 15.38%
Wound: 1 person, 7.69%
Hypersensitivity: 1 person, 7.69%
Asthma: 1 person, 7.69%
Blood Iron Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Surgical failure?

- Check whether Surgical failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Surgical failure:

Surgical failure (140 drugs)

Browse all the conditions that are associated with Surgical failure:

Surgical failure (256 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.