Loratadine and Impaired work ability - a phase IV clinical study of FDA data

Summary:

Impaired work ability is reported as a side effect among people who take Loratadine (loratadine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have Hiv infection.

The phase IV clinical study analyzes which people have Impaired work ability when taking Loratadine. It is created by eHealthMe based on reports of 53,991 people who have side effects when taking Loratadine from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Impaired work ability?

Impaired work ability is found to be associated with 1,013 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Impaired work ability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

53,991 people reported to have side effects when taking Loratadine.
Among them, 74 people (0.14%) have Impaired work ability.

Could Loratadine cause Impaired work ability?

Among these 74 people:

How long have people been on Loratadine when they have Impaired work ability? *

  • < 1 month: 40 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 20 %

What is the gender of people who have Impaired work ability when taking Loratadine? *

  • female: 61.11 %
  • male: 38.89 %

What is the age of people who have Impaired work ability when taking Loratadine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.41 %
  • 30-39: 12.96 %
  • 40-49: 20.37 %
  • 50-59: 24.07 %
  • 60+: 35.19 %

What are other drugs people take besides Loratadine? *

  1. Lisinopril: 16 people, 21.62%
  2. Zyrtec: 13 people, 17.57%
  3. Protonix: 13 people, 17.57%
  4. Azithromycin: 13 people, 17.57%
  5. Levaquin: 13 people, 17.57%
  6. Omeprazole: 12 people, 16.22%
  7. Ambien: 12 people, 16.22%
  8. Flomax: 12 people, 16.22%
  9. Medrol: 11 people, 14.86%
  10. Lyrica: 11 people, 14.86%

What are other side effects people have besides Impaired work ability? *

  1. Pain: 37 people, 50.00%
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 26 people, 35.14%
  3. Fatigue (feeling of tiredness): 26 people, 35.14%
  4. Emotional Distress: 24 people, 32.43%
  5. Stress And Anxiety: 20 people, 27.03%
  6. Back Pain: 18 people, 24.32%
  7. Insomnia (sleeplessness): 16 people, 21.62%
  8. High Blood Pressure: 15 people, 20.27%
  9. Diarrhea: 15 people, 20.27%
  10. Dyspnea (difficult or laboured breathing): 15 people, 20.27%

What are the existing conditions these people have? *

  1. Hiv Infection: 12 people, 16.22%
  2. Pain: 10 people, 13.51%
  3. Diabetes: 9 people, 12.16%
  4. High Blood Pressure: 9 people, 12.16%
  5. Multiple Myeloma (cancer of the plasma cells): 8 people, 10.81%
  6. Sleep Disorder: 8 people, 10.81%
  7. Insomnia (sleeplessness): 7 people, 9.46%
  8. High Blood Cholesterol: 7 people, 9.46%
  9. Hypersensitivity: 7 people, 9.46%
  10. Sinus Disorder (disease of sinus): 7 people, 9.46%

* Approximation only. Some reports may have incomplete information.

Do you take Loratadine and have Impaired work ability?

- Check whether Impaired work ability is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loratadine:

Impaired work ability treatments and more:

How severe was Impaired work ability and when was it recovered:

Expand to all the drugs that have ingredients of loratadine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loratadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired work ability:

Browse all the conditions that are associated with Impaired work ability:


How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Loratadine) and Loratadine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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