Loratadine and Inappropriate antidiuretic hormone secretion - a phase IV clinical study of FDA data

Summary:

Inappropriate antidiuretic hormone secretion is reported as a side effect among people who take Loratadine (loratadine), especially for people who are female, 60+ old, also take Hydrochlorothiazide, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Inappropriate antidiuretic hormone secretion when taking Loratadine. It is created by eHealthMe based on reports of 53,991 people who have side effects when taking Loratadine from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Inappropriate antidiuretic hormone secretion?

Inappropriate antidiuretic hormone secretion is found to be associated with 669 drugs and 1,039 conditions by eHealthMe. Check the latest studies of Inappropriate antidiuretic hormone secretion.

On Aug, 09, 2026

53,991 people reported to have side effects when taking Loratadine.
Among them, 21 people (0.04%) have Inappropriate antidiuretic hormone secretion.

Could Loratadine cause Inappropriate antidiuretic hormone secretion?

Among these 21 people:

What is the gender of people who have Inappropriate antidiuretic hormone secretion when taking Loratadine? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Inappropriate antidiuretic hormone secretion when taking Loratadine? *

What are other drugs people take besides Loratadine? *

Hydrochlorothiazide: 4 people, 19.05%
Lipitor: 3 people, 14.29%
Ranitidine Hydrochloride: 3 people, 14.29%
Synthroid: 3 people, 14.29%
Nexium: 2 people, 9.52%
Methotrexate: 2 people, 9.52%
Megestrol Acetate: 2 people, 9.52%
Lorazepam: 2 people, 9.52%
Levoxyl: 2 people, 9.52%
Levofloxacin: 2 people, 9.52%

What are other side effects people have besides Inappropriate antidiuretic hormone secretion? *

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 7 people, 33.33%
High Blood Pressure: 6 people, 28.57%
Weakness: 4 people, 19.05%
Joint Pain: 4 people, 19.05%
Thrombocytopenia (decrease of platelets in blood): 4 people, 19.05%
Nausea (feeling of having an urge to vomit): 4 people, 19.05%
Pain: 4 people, 19.05%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 19.05%
Diarrhea: 4 people, 19.05%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 14.29%

What are the existing conditions these people have? *

Cardiac Disorder: 3 people, 14.29%
Hypersensitivity: 3 people, 14.29%
Itching: 2 people, 9.52%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
Thyroid Diseases: 2 people, 9.52%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 9.52%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 9.52%
Blood Count Abnormal: 1 person, 4.76%
Breast Cancer: 1 person, 4.76%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Loratadine and have Inappropriate antidiuretic hormone secretion?

- Check whether Inappropriate antidiuretic hormone secretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loratadine:

Loratadine (56,314 reports)

Inappropriate antidiuretic hormone secretion treatments and more:

Inappropriate antidiuretic hormone secretion (11,995 reports)

How severe was Inappropriate antidiuretic hormone secretion and when was it recovered:

Inappropriate antidiuretic hormone secretion in Loratadine

Expand to all the drugs that have ingredients of loratadine:

Inappropriate antidiuretic hormone secretion and drugs with ingredients of loratadine

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loratadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Inappropriate antidiuretic hormone secretion:

Inappropriate antidiuretic hormone secretion (669 drugs)

Browse all the conditions that are associated with Inappropriate antidiuretic hormone secretion:

Inappropriate antidiuretic hormone secretion (1,039 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Loratadine) and Loratadine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.