Loratadine and Streptococcal sepsis - a phase IV clinical study of FDA data

Summary:

Streptococcal sepsis is reported as a side effect among people who take Loratadine (loratadine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Phenergan, and have Diffuse large b-cell lymphoma stage iv.

The phase IV clinical study analyzes which people have Streptococcal sepsis when taking Loratadine. It is created by eHealthMe based on reports of 53,991 people who have side effects when taking Loratadine from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Streptococcal sepsis?

Streptococcal sepsis (whole body inflammation by streptococcal) is found to be associated with 333 drugs and 359 conditions by eHealthMe. Check the latest studies of Streptococcal sepsis.

On Jul, 16, 2026

53,991 people reported to have side effects when taking Loratadine.
Among them, 17 people (0.03%) have Streptococcal sepsis.

Could Loratadine cause Streptococcal sepsis?

Among these 17 people:

How long have people been on Loratadine when they have Streptococcal sepsis? *

What is the gender of people who have Streptococcal sepsis when taking Loratadine? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Streptococcal sepsis when taking Loratadine? *

What are other drugs people take besides Loratadine? *

Phenergan: 12 people, 70.59%
Dexamethasone: 11 people, 64.71%
Escitalopram: 11 people, 64.71%
Acetaminophen: 10 people, 58.82%
Mirtazapine: 10 people, 58.82%
Valacyclovir Hydrochloride: 10 people, 58.82%
Carboplatin: 10 people, 58.82%
Cytarabine: 10 people, 58.82%
Fluconazole: 10 people, 58.82%
Furosemide: 10 people, 58.82%

What are other side effects people have besides Streptococcal sepsis? *

Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 12 people, 70.59%
Infectious Pleural Effusion (infectious fluid in the lung): 3 people, 17.65%
High Blood Cholesterol: 2 people, 11.76%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 11.76%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 11.76%
Blood Bilirubin Increased: 2 people, 11.76%
Pleuritic Pain: 2 people, 11.76%
Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 2 people, 11.76%
Insomnia (sleeplessness): 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%

What are the existing conditions these people have? *

Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 11 people, 64.71%
Nausea (feeling of having an urge to vomit): 4 people, 23.53%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 17.65%
Aortic Stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 3 people, 17.65%
Back Pain: 3 people, 17.65%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 17.65%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 3 people, 17.65%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
High Blood Pressure: 3 people, 17.65%
Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Loratadine and have Streptococcal sepsis?

- Check whether Streptococcal sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loratadine:

Loratadine (56,314 reports)

Browse all side effects of Loratadine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Streptococcal sepsis:

Streptococcal sepsis (333 drugs)

Browse all the conditions that are associated with Streptococcal sepsis:

Streptococcal sepsis (359 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Loratadine) and Loratadine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.