Loraz and Brain death - a phase IV clinical study of FDA data

Summary:

Brain death is reported as a side effect among people who take Loraz (lorazepam), especially for people who are female, 20-29 old, also take Ondansetron, and have Nausea.

The study is created by eHealthMe based on reports of 161,700 people who have side effects when taking Loraz from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

On Aug, 12, 2026

161,700 people reported to have side effects when taking Loraz.
Among them, 96 people (0.06%) died.

Among these 96 people:

What is the gender of people who died when taking Loraz? *

female: 80.23 %
male: 19.77 %

What is the age of people who died when taking Loraz? *

What are other drugs people take besides Loraz? *

What are other side effects people have before they died? *

Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 36 people, 37.50%
Cardiac Arrest: 35 people, 36.46%
Consciousness - Decreased: 29 people, 30.21%
Head Injury: 28 people, 29.17%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 27 people, 28.12%
Hypoxic-Ischaemic Encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total): 24 people, 25.00%
Arrhythmias (irregular heartbeat): 24 people, 25.00%
Pneumonia: 22 people, 22.92%
Torsade De Pointes (a abnormal heart rate with abnormal beating pattern): 20 people, 20.83%
Ventricular Fibrillation (abnormally irregular heart rhythm): 20 people, 20.83%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 19 people, 19.79%
Nausea And Vomiting: 18 people, 18.75%
Cyclic Vomiting Syndrome (prolonged episodes of severe nausea, vomiting): 16 people, 16.67%
Completed Suicide (act of taking one's own life): 8 people, 8.33%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 7.29%
Sedation: 7 people, 7.29%
Electrocardiogram Qt Prolonged: 7 people, 7.29%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 4.17%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 3.12%
Diabetes: 3 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loraz:

Loraz (165,695 reports)

Expand to all the drugs that have ingredients of lorazepam:

Brain death and drugs with ingredients of lorazepam (113 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain death:

Brain death (315 drugs)

Browse all the conditions that are associated with Brain death:

Brain death (489 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Loraz) and Loraz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.