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Loraz and Hypertrophic cardiomyopathy - a phase IV clinical study of FDA data

Summary:

Hypertrophic cardiomyopathy is reported as a side effect among people who take Loraz (lorazepam), especially for people who are female, 0-1 old, have been taking the drug for < 1 month also take Midazolam, and have Local anaesthesia.

The phase IV clinical study analyzes which people have Hypertrophic cardiomyopathy when taking Loraz. It is created by eHealthMe based on reports of 161,700 people who have side effects when taking Loraz from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

What is Hypertrophic cardiomyopathy?

Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick) is found to be associated with 263 drugs and 945 conditions by eHealthMe. Check the latest studies of Hypertrophic cardiomyopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 28, 2026

161,700 people reported to have side effects when taking Loraz.
Among them, 36 people (0.02%) have Hypertrophic cardiomyopathy.

Could Loraz cause Hypertrophic cardiomyopathy?

Among these 36 people:

How long have people been on Loraz when they have Hypertrophic cardiomyopathy? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypertrophic cardiomyopathy when taking Loraz? *

  • female: 72.22 %
  • male: 27.78 %

What is the age of people who have Hypertrophic cardiomyopathy when taking Loraz? *

  • 0-1: 50.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.76 %
  • 50-59: 11.76 %
  • 60+: 26.47 %

What are other drugs people take besides Loraz? *

  1. Midazolam: 17 people, 47.22%
  2. Hydrodiuril: 16 people, 44.44%
  3. Furosemide: 8 people, 22.22%
  4. Magnesium Sulfate: 6 people, 16.67%
  5. Morphine: 6 people, 16.67%
  6. Albuterol: 5 people, 13.89%
  7. Metoclopramide: 4 people, 11.11%
  8. Bivalirudin: 4 people, 11.11%
  9. Lidocaine: 4 people, 11.11%
  10. Protamine Sulfate: 4 people, 11.11%

What are other side effects people have besides Hypertrophic cardiomyopathy? *

  1. Hypokalemia (low potassium): 18 people, 50.00%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 18 people, 50.00%
  3. Abnormal Behavior: 17 people, 47.22%
  4. Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased): 17 people, 47.22%
  5. Kidney Stones: 17 people, 47.22%
  6. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 17 people, 47.22%
  7. Pulmonary Hypertension (increase in blood pressure in the lung artery): 17 people, 47.22%
  8. Pathological Fracture (broken bone caused by disease): 17 people, 47.22%
  9. Hypochloraemia (electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood): 17 people, 47.22%
  10. Cor Pulmonale (enlargement of the right ventricle of the heart): 17 people, 47.22%

What are the existing conditions these people have? *

  1. Urination - Excessive Volume: 2 people, 5.56%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 5.56%
  3. Anaesthesia: 2 people, 5.56%
  4. Asthma: 2 people, 5.56%
  5. Cardiotoxicity (damage to the heart muscle): 2 people, 5.56%
  6. Central Nervous System Stimulation: 2 people, 5.56%
  7. Constipation: 2 people, 5.56%
  8. Gastritis (inflammation of stomach): 2 people, 5.56%
  9. Herpes Zoster: 2 people, 5.56%
  10. Local Anaesthesia: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and have Hypertrophic cardiomyopathy?

- Check whether Hypertrophic cardiomyopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loraz:

  • Loraz (165,695 reports)

Hypertrophic cardiomyopathy treatments and more:

How severe was Hypertrophic cardiomyopathy and when was it recovered:

Expand to all the drugs that have ingredients of lorazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertrophic cardiomyopathy:

Browse all the conditions that are associated with Hypertrophic cardiomyopathy:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Loraz) and Loraz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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