Loraz and Optic neuropathy - a phase IV clinical study of FDA data
Summary:
Optic neuropathy is reported as a side effect among people who take Loraz (lorazepam), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Metformin, and have Rheumatoid arthritis.
The phase IV clinical study analyzes which people have Optic neuropathy when taking Loraz. It is created by eHealthMe based on reports of 161,700 people who have side effects when taking Loraz from the FDA, and is updated regularly.
What is Loraz?
Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.
What is Optic neuropathy?
Optic neuropathy (optic nerve damage) is found to be associated with 258 drugs and 451 conditions by eHealthMe. Check the latest studies of Optic neuropathy.
161,700 people reported to have side effects when taking Loraz.
Among them, 30 people (0.02%) have Optic neuropathy.

Among these 30 people:
How long have people been on Loraz when they have Optic neuropathy? *
- < 1 month: 0.0 %
- 1 - 6 months: 33.33 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 66.67 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Optic neuropathy when taking Loraz? *
- female: 76.92 %
- male: 23.08 %
What is the age of people who have Optic neuropathy when taking Loraz? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 4.35 %
- 20-29: 8.7 %
- 30-39: 4.35 %
- 40-49: 4.35 %
- 50-59: 34.78 %
- 60+: 43.48 %
What are other drugs people take besides Loraz? *
- Mestinon: 16 people, 53.33%
- Vitamin B6: 16 people, 53.33%
- Estrogel: 16 people, 53.33%
- Metformin: 16 people, 53.33%
- Clonazepam: 11 people, 36.67%
- Acetaminophen: 11 people, 36.67%
- Progesterone: 10 people, 33.33%
- Methotrexate: 10 people, 33.33%
- Testosterone: 10 people, 33.33%
- Methylprednisolone: 10 people, 33.33%
What are other side effects people have besides Optic neuropathy? *
- Fall: 18 people, 60.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 18 people, 60.00%
- Headache (pain in head): 18 people, 60.00%
- Pain: 18 people, 60.00%
- Dyspnea (difficult or laboured breathing): 17 people, 56.67%
- Hepatic Steatosis (fatty liver disease): 17 people, 56.67%
- Drug Ineffective: 17 people, 56.67%
- Hordeolum (small collection of pus (abscess) on the eyelid): 16 people, 53.33%
- The Flu (the flu is caused by an influenza virus): 16 people, 53.33%
- Fibromyalgia (a long-term condition which causes pain all over the body): 16 people, 53.33%
What are the existing conditions these people have? *
- Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 16 people, 53.33%
- Diabetes: 16 people, 53.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 53.33%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 13.33%
- Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 4 people, 13.33%
- Muscle Twitching: 4 people, 13.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 13.33%
- Dry Eyes (lack of adequate tears): 3 people, 10.00%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 10.00%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Loraz and have Optic neuropathy?
- Check whether Optic neuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Loraz:
- Loraz (165,694 reports)
Optic neuropathy treatments and more:
- Optic neuropathy (2,298 reports)
How severe was Optic neuropathy and when was it recovered:
Expand to all the drugs that have ingredients of lorazepam:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Loraz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Optic neuropathy:
- Optic neuropathy (258 drugs)
Browse all the conditions that are associated with Optic neuropathy:
- Optic neuropathy (451 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lorazepam (the active ingredients of Loraz) and Loraz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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