Loraz and Sinus arrhythmia - a phase IV clinical study of FDA data

Summary:

Sinus arrhythmia is reported as a side effect among people who take Loraz (lorazepam), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Alprazolam, and have High blood pressure.

The phase IV clinical study analyzes which people have Sinus arrhythmia when taking Loraz. It is created by eHealthMe based on reports of 161,700 people who have side effects when taking Loraz from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

What is Sinus arrhythmia?

Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle) is found to be associated with 361 drugs and 418 conditions by eHealthMe. Check the latest studies of Sinus arrhythmia.



On Aug, 08, 2026

161,700 people reported to have side effects when taking Loraz.
Among them, 34 people (0.02%) have Sinus arrhythmia.

Could Loraz cause Sinus arrhythmia?

Among these 34 people:

How long have people been on Loraz when they have Sinus arrhythmia? *

  • < 1 month: 70 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 20 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus arrhythmia when taking Loraz? *

  • female: 61.76 %
  • male: 38.24 %

What is the age of people who have Sinus arrhythmia when taking Loraz? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 0.0 %
  • 30-39: 9.09 %
  • 40-49: 9.09 %
  • 50-59: 15.15 %
  • 60+: 57.58 %

What are other drugs people take besides Loraz? *

  1. Alprazolam: 6 people, 17.65%
  2. Dexamethasone: 5 people, 14.71%
  3. Alcohol: 5 people, 14.71%
  4. Aspirin: 5 people, 14.71%
  5. Omeprazole: 5 people, 14.71%
  6. Lopressor: 5 people, 14.71%
  7. Zometa: 4 people, 11.76%
  8. Lovenox: 4 people, 11.76%
  9. Folic Acid: 4 people, 11.76%
  10. Cozaar: 4 people, 11.76%

What are other side effects people have besides Sinus arrhythmia? *

  1. Chest Pain: 10 people, 29.41%
  2. Fatigue (feeling of tiredness): 9 people, 26.47%
  3. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 9 people, 26.47%
  4. Heart Attack: 8 people, 23.53%
  5. Fainting (loss of consciousness and postural tone): 7 people, 20.59%
  6. Nausea (feeling of having an urge to vomit): 7 people, 20.59%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 6 people, 17.65%
  8. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 6 people, 17.65%
  9. Cardiac Failure Congestive: 6 people, 17.65%
  10. Electrocardiogram Qt Prolonged: 6 people, 17.65%

What are the existing conditions these people have? *

  1. Pain: 3 people, 8.82%
  2. High Blood Pressure: 3 people, 8.82%
  3. Sleep Disorder: 2 people, 5.88%
  4. Fever: 2 people, 5.88%
  5. Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 2 people, 5.88%
  6. Nausea (feeling of having an urge to vomit): 2 people, 5.88%
  7. Oral Herpes (viral infection of mouth): 2 people, 5.88%
  8. Cold Type Haemolytic Anaemia (anaemia of abnormal breakdown of red blood cells): 2 people, 5.88%
  9. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 5.88%
  10. Anaemia (lack of blood): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and have Sinus arrhythmia?

- Check whether Sinus arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loraz:

  • Loraz (165,695 reports)

Sinus arrhythmia treatments and more:

How severe was Sinus arrhythmia and when was it recovered:

Expand to all the drugs that have ingredients of lorazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus arrhythmia:

Browse all the conditions that are associated with Sinus arrhythmia:


How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Loraz) and Loraz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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