Lorcet-hd and Osteomyelitis - a phase IV clinical study of FDA data

Summary:

Osteomyelitis is reported as a side effect among people who take Lorcet-hd (acetaminophen; hydrocodone bitartrate), especially for people who are female, 60+ old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Osteomyelitis when taking Lorcet-hd. It is created by eHealthMe based on reports of 2,140 people who have side effects when taking Lorcet-hd from the FDA, and is updated regularly.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

What is Osteomyelitis?

Osteomyelitis (infection of bone) is found to be associated with 1,420 drugs and 1,330 conditions by eHealthMe. Check the latest studies of Osteomyelitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

2,140 people reported to have side effects when taking Lorcet-hd.
Among them, 59 people (2.76%) have Osteomyelitis.

Among these 59 people:

What is the gender of people who have Osteomyelitis when taking Lorcet-hd? *

female: 52.54 %
male: 47.46 %

What is the age of people who have Osteomyelitis when taking Lorcet-hd? *

What are other drugs people take besides Lorcet-hd? *

What are other side effects people have besides Osteomyelitis? *

Anaemia (lack of blood): 43 people, 72.88%
Osteonecrosis Of Jaw (death of bone of jaw): 37 people, 62.71%
Fatigue (feeling of tiredness): 35 people, 59.32%
Pain In Extremity: 34 people, 57.63%
Osteitis (a general term for inflammation of bone): 34 people, 57.63%
Impaired Healing: 33 people, 55.93%
Chest Pain: 32 people, 54.24%
Weight Decreased: 32 people, 54.24%
Constipation: 30 people, 50.85%
Fainting (loss of consciousness and postural tone): 29 people, 49.15%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 18 people, 30.51%
Depression: 9 people, 15.25%
Constipation: 8 people, 13.56%
Stress And Anxiety: 8 people, 13.56%
Bone Density Decreased: 7 people, 11.86%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 8.47%
Resorption Bone Increased: 5 people, 8.47%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 8.47%
Oral Candidiasis (fungal infection of mouth): 5 people, 8.47%
High Blood Pressure: 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

Do you take Lorcet-hd and have Osteomyelitis?

- Check whether Osteomyelitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lorcet-hd:

Lorcet-hd (2,221 reports)

Osteomyelitis treatments and more:

Osteomyelitis (34,172 reports)

How severe was Osteomyelitis and when was it recovered:

Osteomyelitis in Lorcet-hd

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Osteomyelitis and drugs with ingredients of acetaminophen; hydrocodone bitartrate (1,753 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lorcet-hd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteomyelitis:

Osteomyelitis (1,420 drugs)

Browse all the conditions that are associated with Osteomyelitis:

Osteomyelitis (1,330 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Lorcet-hd) and Lorcet-hd (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.