Lortab and Cervical spinal stenosis - a phase IV clinical study of FDA data

Summary:

Cervical spinal stenosis is reported as a side effect among people who take Lortab (acetaminophen; hydrocodone bitartrate), especially for people who are 40-49 old, also take Zofran, and have Metastases to bone.

The phase IV clinical study analyzes which people have Cervical spinal stenosis when taking Lortab. It is created by eHealthMe based on reports of 29,547 people who have side effects when taking Lortab from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Cervical spinal stenosis?

Cervical spinal stenosis (narrowing of the spinal canal in the neck) is found to be associated with 587 drugs and 514 conditions by eHealthMe. Check the latest studies of Cervical spinal stenosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

29,547 people reported to have side effects when taking Lortab.
Among them, 55 people (0.19%) have Cervical spinal stenosis.

Could Lortab cause Cervical spinal stenosis?

Among these 55 people:

What is the age of people who have Cervical spinal stenosis when taking Lortab? *

What are other drugs people take besides Lortab? *

What are other side effects people have besides Cervical spinal stenosis? *

Stress And Anxiety: 44 people, 80.00%
Nausea (feeling of having an urge to vomit): 40 people, 72.73%
Spinal Osteoarthritis (joint cartilage loss in spine): 40 people, 72.73%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 38 people, 69.09%
Injury: 37 people, 67.27%
Depression: 36 people, 65.45%
Neck Pain: 34 people, 61.82%
Osteonecrosis Of Jaw (death of bone of jaw): 34 people, 61.82%
Dyspnea (difficult or laboured breathing): 32 people, 58.18%
Metastases To Bone (cancer spreads to bone): 27 people, 49.09%

What are the existing conditions these people have? *

Bone Loss: 12 people, 21.82%
Metastases To Bone (cancer spreads to bone): 12 people, 21.82%
Bone Density Abnormal: 8 people, 14.55%
Osteoporosis (bones weak and more likely to break): 5 people, 9.09%
Breast Cancer: 4 people, 7.27%
Anaemia (lack of blood): 3 people, 5.45%
Diabetes: 2 people, 3.64%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 3.64%
Breast Cancer Metastatic: 2 people, 3.64%
Confusional State: 2 people, 3.64%

* Approximation only. Some reports may have incomplete information.

Do you take Lortab and have Cervical spinal stenosis?

- Check whether Cervical spinal stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lortab:

Lortab (31,285 reports)

Cervical spinal stenosis treatments and more:

Cervical spinal stenosis (3,283 reports)

How severe was Cervical spinal stenosis and when was it recovered:

Cervical spinal stenosis in Lortab

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Cervical spinal stenosis and drugs with ingredients of acetaminophen; hydrocodone bitartrate (281 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cervical spinal stenosis:

Cervical spinal stenosis (587 drugs)

Browse all the conditions that are associated with Cervical spinal stenosis:

Cervical spinal stenosis (514 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Lortab) and Lortab (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.