Lortab and Tibia fracture - a phase IV clinical study of FDA data

Summary:

Tibia fracture is reported as a side effect among people who take Lortab (acetaminophen; hydrocodone bitartrate), especially for people who are female, 50-59 old, also take Lasix, and have Osteoporosis.

The phase IV clinical study analyzes which people have Tibia fracture when taking Lortab. It is created by eHealthMe based on reports of 29,547 people who have side effects when taking Lortab from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Tibia fracture?

Tibia fracture (fracture of lower leg bone) is found to be associated with 645 drugs and 669 conditions by eHealthMe. Check the latest studies of Tibia fracture.

On Jul, 19, 2026

29,547 people reported to have side effects when taking Lortab.
Among them, 55 people (0.19%) have Tibia fracture.

$Could Lortab cause Tibia fracture?$

Among these 55 people:

What is the gender of people who have Tibia fracture when taking Lortab? *

female: 84.91 %
male: 15.09 %

What is the age of people who have Tibia fracture when taking Lortab? *

What are other drugs people take besides Lortab? *

What are other side effects people have besides Tibia fracture? *

Stress And Anxiety: 45 people, 81.82%
Depression: 38 people, 69.09%
Fall: 36 people, 65.45%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 35 people, 63.64%
Injury: 33 people, 60.00%
Rib Fracture: 30 people, 54.55%
Atelectasis (partial or complete collapse of the lung): 29 people, 52.73%
Osteonecrosis Of Jaw (death of bone of jaw): 29 people, 52.73%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 29 people, 52.73%
Mastication Disorder (disease of chewing food): 28 people, 50.91%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 12 people, 21.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 20.00%
High Blood Pressure: 9 people, 16.36%
Stress And Anxiety: 8 people, 14.55%
Bone Density Abnormal: 8 people, 14.55%
Multiple Myeloma (cancer of the plasma cells): 6 people, 10.91%
Bone Disorder: 6 people, 10.91%
Indigestion: 4 people, 7.27%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 5.45%
Breast Cancer Metastatic: 2 people, 3.64%

* Approximation only. Some reports may have incomplete information.

Do you take Lortab and have Tibia fracture?

- Check whether Tibia fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lortab:

Lortab (31,285 reports)

Tibia fracture treatments and more:

Tibia fracture (6,376 reports)

How severe was Tibia fracture and when was it recovered:

Tibia fracture in Lortab

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Tibia fracture and drugs with ingredients of acetaminophen; hydrocodone bitartrate (239 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tibia fracture:

Tibia fracture (645 drugs)

Browse all the conditions that are associated with Tibia fracture:

Tibia fracture (669 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Lortab) and Lortab (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.